Rector

Rosario Rizzuto

Full Professor, Department of Biomedical Sciences
Secretariat: Via 8 Febbraio 2 -  35122 Padova (Italy)
phone.:+39 049 827 3001 - fax: +39 049 827 3009
email: rettore@unipd.it

Rosario RIZZUTO, MD PhD, is Professor of General Pathology. He was Director of the Department of Biomedical Sciences and member of the University Senate of the University of Padua (Italy). He became Lecturer in Padua in 1992, then Professor in Ferrara in 1998 (where he was Director of the Emilia Romagna Genetics and Biotechnology network, Dean of the Pharmacy School and member of the University Senate). In 2008, he returned to the University of Padua, as Professor of the Medical Faculty. He was elected as the University's Rector on October 1st 2015.

His research interests have been centered on the study of cellular signalling, with special focus on intracellular calcium homeostasis. He developed an innovative methodology, organelle targeting of recombinant luminescent (aequorin, luciferase) and fluorescent (GFP) proteins, that allowed novel insight in the fields of calcium signalling, cellular metabolism and organelle morphology. New concepts were acquired, which include the participation of mitochondria in cellular Ca2+ homeostasis and their role in translating calcium signals in effects as diverse as stimulation of metabolism and induction of cell death, the occurrence of tight signalling interactions between the endoplasmic reticulum and mitochondria, the identification of the Golgi apparatus as an agonist-sensitive Ca2+ store, and the major Ca2+ rises occurring under the plasma membrane upon cell stimulation, to cite a few. In 2011, Prof. Rizzuto identified the mitochondrial calcium uniporter (MCU), the only fundamental component of the cellular calcium signalling machinery yet to be discovered. This result has opened the molecular era of mitochondrial Ca2+ homeostasis, that combines molecular insight into the structure/function relationship of MCU and its regulators and the possibility of manipulating mitochondrial Ca2+ handling in cultured cells and animal models, with the goal of clarifying its role in the physiological regulation of tissues and in the pathogenesis of the most prevalent human diseases (neurodegenerative disorders, ischemic heart disease, cancer).

Prof. Rizzuto published 280 papers in international peer-reviewed journals.

According to Google scholar, H-index is 106, with more than 39.000 total citations. According to Scopus, H-index is 90, with more than 29.000 total citations.

His work is funded by EU (ERC Ideas), charities (AIRC, Telethon), state agencies (FIRB, Health Ministry), bank foundations (Cariparo, Cariplo). He is member of the Academia Europaea and EMBO, and acts as reviewer for high IF journals (Nature, Science, Cell, etc.) and international funding agencies. He was awarded the Chiara D’Onofrio prize, the Biotec award, the Theodor Bucher medal and the Antonio Feltrinelli Prize. 


10 selected publications of the last 10 years

 

 

 

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NEWS

Cambridge University, MBU - The 5th Annual Sir John Walker Lecture has been delivered by Professor Rosario Rizzuto.

10 May 2017

In 2011, Professor Rizzuto identified the mitochondrial calcium uniporter (MCU), the only fundamental component of the cellular calcium signalling machinery yet to be discovered (De Stefani et al., Nature 476, 338-340, 2011). This result has opened the molecular era of mitochondrial Ca2+ homeostasis, that combines molecular insight into the structure/function relationship of MCU and its regulators (Raffaello et al., EMBO J. 32, 2362-2376; Patron et al. Mol. Cell 53, 726-37) and the possibility of manipulating mitochondrial Ca2+ handling in cultured cells and animal models, to clarify its role in the physiological regulation of tissues and in the pathogenesis of the most prevalent human diseases (neurodegenerative disorders, ischemic heart disease, cancer). 

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Speaking at the European Parliament in Brussels

9 May 2017

Speaking at the European Parliament in Brussels in May 11, 2017, the rector of the University of Padova, Rosario Rizzuto, recalled the unique history of our University: eight centuries of teaching and research, of freedom and cultural growth that brought to Padova the most distinguished scholars and students of Europe. An unbroken tradition of dedication to knowledge that links those scholars who came before us with those of future generations.

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Gordon Research Conference

21 June 2017

Rosario Rizzuto spoke at the Gordon Research Conference "Intracellular Calcium Signals: Generation, Function and Therapeutic Intervention" in Lucca with the keynote "Mitochondria: Conductors of the Calcium Orchestra"

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The ERC meeting hosted in Padua. What is the role of frontier research?

26 April 2017

In April 2017 the University of Padua hosted the meeting "The European Research Council and the impact of frontier research" in order to discuss the role of scientific research, its future and its central role in promoting innovation. Conference speakers list included: Rosario Rizzuto, Rector of the University of Padua; Jean Pierre Bourguignon, President of the European Research Council; Patrick Aebischer, former chairman of the EPFL in Lausanne; Mario Monti, Rector of Bocconi University and chairman of the "High Level Group on Own Resources” (EU).

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