The main area of interest has been protein kinases, and in particular protein kinase CK1 and CK2. The main research field regards the study of the molecular and cellular mechanisms regulating by alteration of protein kinases signalling. Other research field has been the identification, development and characterization of new compounds able to affect protein kinases as pharmacological targets. In the last years he has devoted his attention to the Cystic Fibrosis and in particular to protein kinases deregulation in this pathology with a good publications record as well as funded grants. In addition, he studied the cellular and molecular mechanisms that involve the F508delCFTR mutation, particularly its function, stability and trafficking at plasma membrane. He has devoted his attention to test new “natural” compound to regulate function and stability of CFTR at PM. Currently, he is studying new biotechnological applications of peculiar iron oxide nanoparticles, named Surface Active Maghemite Nanoparticles (SAMN), in the field of cell tracking, target driven drug delivery and purification of biomolecules from complex biological and environmental samples.