ERC: Massimo Santoro

Download Project: rEnDOx- Redox Signaling and Metabolic States in Angiogenesis in Health and Disease

Massimo Santoro


ERC Grantee: Massimo Santoro

Department: Biology

Total Contribution: Euro 1.999.827,00

Project Duration in months: 60

Start Date: 01/07/2016
End Date: 30/06/2021

Personal page


Massimo Mattia Santoro is Full Professor and Chair of Cell Biology at Department of Biology of the University of Padua.

Massimo Santoro obtained his Master Diploma from University of Turin (Italy), and his PhD in Molecular and Cellular Biology from the Open University, London (UK). He worked as a post-doc fellow at University of California, San Francisco (USA), with Prof. Dr. Didier Stainier, where he became interested in cardiovascular development and endothelial homeostasis. In 2008, he established his first independent laboratory at the University of Torino, opening the Molecular Biotechnology Center. In 2013 he was appointed VIB Group Leader and Full Professor at Vesalius Research Center at the University of Leuven (Belgium). In 2017, he returned to Italy at University of Padua as Chair of Cell Biology at Department of Biology. During his career, he has been granted with the EMBO (2004) and HFSP (2005) long-term fellowships, the HFSP Career Developmental Award (2008), the Marie Curie Reintegration Grant (2010), the Odysseus-FWO Career Grant (2014), and, more recently, the ERC Consolidator Grant (2016). His lab is currently focused on studying how redox signaling, metabolism, and hemodynamic forces regulates endothelial homeostasis in development as well as during cancer progression. To accomplish this goal his lab is taking advantage of innovative genetic and imaging technologies as well as new molecular and biochemical approaches in vertebrate models, such as zebrafish and mouse. Massimo’s goal is to expand the current vision of endothelial biology by identifying unforeseen metabolic and signaling mechanisms and used them to develop novel anti-angiogenesis therapies to treat cancer progression and diabetic conditions. His research is supported by national bodies and private foundations (e.g., Italian Ministry of Education and Research, Telethon, AIRC). He sits on several scientific advisory boards and reviewing panels. He is an Editorial Board member of Cancers, Cardiovasc Res, Scientific Reports, Frontiers in Cell and Developmental Biology.