PhD Course

Pharmacological Sciences

Thematic area Medical and Biomedical Sciences
Duration 3 years
Language Italian
English
PhD Programme Coordinator Nicola Ferri

The PhD course provides qualified training in the pharmacological, toxicological and therapeutic fields, the course includes basic research and applied research at a clinical and epidemiological level.

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Planned Teaching activities:

First year
- Course on "Information Literacy in Pharmacological Sciences"
- Course on "Bio-Statistics"

Second year
- Course on “Academic English for PhD Students”, at Centro Linguistico di Ateneo
- "Advanced Pharmacology" course consisting of 5 modules each: 1) Pharmacokinetics 2) Clinical biochemistry 3) Methods in Molecular Pharmacology 4) Application aspects of clinical research methodology 5) Neuropharmacology.

Third year
- Teaching of "Communicating Science Effectively".
Several seminars (approximately once a month) will also be organized and held by English-speaking scientists.
PhD students are required to attend at least 70% of the training activities offered and pass the evaluation test.

The mission of the 3 years PhD Course in Pharmacological Sciences is to prepare new young generation of scientists with a solid background in the field of Molecular Pharmacology, Clinical Pharmacology, Pharmacoepidemiology and Toxicology. To this purposes the PhD scholar program is organized in two parallel curricula:  Molecular and Cellular Pharmacology,  Pharmacology, Toxicology and Therapeutics

- Role of multiproteic complex NLRP3 inflammosome and dietary habits in central and peripheral inflammatory processes in Parkinson disease;
- Development of innovative therapies for chemotherapy-treated prostate cancer;
- Development of senolytics of natural origin for anti-aging therapy;
- Targeting melatonin receptors for neuropsychiatric disorders;
- Pharmacological modulation of age-related vascular pathologies;
- Study of metabolic reprogramming and identification of innovative pharmacological targets in chemotherapy resistance;
- Study of possible hormonal implications in Sars-CoV-2 virus infection and disease progression;
- Risk assessment of combined chemical exposures;
- Long COVID-19 asymptomatic or pauci-symptomatic and biological aging;
- Correlation Between Concentration at the Effector Site of Ketamine (Calculated With DOMINO Pump) and Bispectral Index Values During General Anaesthesia for Breast Surgery;
- Sex differences in immune checkpoint expression and release by human endothelial cells and monocyte-derived macrophages: implications for combined personalized therapies;
- Investigating novel immunotherapy strategies to treat liver cancer;
- Surveillance of healthcare workers for SARS-CoV-2 infection and testing of a clinical follow-up model;
- Role of Toll like receptor 4 in opioid-induced microglia activation and tolerance.

Research lines - Molecular and Cellular Pharmacology
- Neuro-degenerative disorders: molecular mechanisms, genetics, and studies of therapeutic interventions
- Autonomic nervous system on bronchial function, new pharmacological agents
- Enteric nervous system and immune system, search for therapeutic targets
- Cardiovascular diseases, aging, gender and pharmacological responses
- Antitumoral compounds and mechanisms in drug resistance
- Metabolomics and lipidomics studies to the identification of new drug targets
- Immune system and search for molecular pharmacological targets
- Pharmacological modulation of chronic inflammatory diseases
- Medicinal plants as source of pharmacological agents
- Phenotyping/genotyping and therapeutic monitoring to develop new diagnostic screening tests
- Pharmacokinetic studies in healthy and disease

Research lines - Pharmacology, Toxicology and Therapeutics
- Critical care therapy. Pain therapies, both intensive and hyperbaric
- Risk prevention and occupational medicine
- Airway inflammation induced by inhaled pollutants
- Environmental toxicology xenobiotics in the urban water cycle
- Development of new environmentally friendly and species-selective pesticides
- Clinical pharmacology and therapeutic drug monitoring
- Pharmacoepidemiology
- Pharmacoeconomics
- Pharmacovigilance

  Contacts

nicola.ferri@unipd.it