MSCA PF Fellow: Elena Monti

PDFProject:  RestorAGING - A novel role for PGE2 signalling in promoting aged neuromuscular junctions reinnervation and counteracting sarcopenia

Elena Monti


MSCA Fellow: Elena Monti

UNIPD Supervisor:  Marco Narici

Department:  Biomedical Sciences

Total Contribution:  Euro 265.099,19

Project Duration in months: 36

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Elena Monti obtained her B.Sc. and M.Sc. in Sport Science at the University of Milan, where she received the ‘Exploit your talent’ scholarship dedicated to distinguished students. During her master, she was a visiting student at the University of Nottingham (UK), where she run a project aimed at investigating the effects of training on aged people’s skeletal muscles. Elena continued her research on the human neuromuscular system adaptations to aging, exercise and disuse during her Ph.D. with Prof. Marco Narici at the University of Padua, where she was trained to learn molecular biology techniques. She currently is a postdoctoral fellow at Stanford University (US) in Prof. Helen Blau lab, where she expanded her work on aging to rodents and humans. RestorAGING, the MSCA project that Elena will run at both Stanford University and UNIPD, aims at investigating the role of an aging-promoting enzyme (15-PGDH) in human aging through sequencing and protein localization, and the effects of 15-PGDH inhibition on the aged mice neuromuscular system. This will pave the way for novel treatments willing to slow down the natural decline in muscle mass and strength that accompanies aging.