MSCA PF Fellow: Natasa Djalinac

PDFProject:  ACCURACY - Human cardiac microtissues for studying lamin cardiomyopathy

Natasa Djalinac


MSCA Fellow: Natasa Djalinac

UNIPD Supervisor: Milena Bellin

Department: Biology

Total Contribution: Euro172.750,08

Project Duration in months: 24

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Nataša Đalinac obtained her BSC and MSc degree in Molecular Biology from the Faculty of Sciences University of Novi Sad, Serbia. Later she relocated to the Medical University of Graz, Austria to pursue a PhD degree in Molecular Medicine. As part of the training within the Division of Cardiology of the Medical University of Graz she gained a strong background in molecular and functional characterization of cardiac remodeling, specifically, excitation contraction coupling in murine and human specimens under supervision of Dr Egbert Bisping and later as part of her post-doctoral period with PhD Senka Ljubojevic-Holzer.  During this time is when she further got interested in the field of translational medicine and bioengineering and thereby used the opportunity to join the team of Prof. Milena Bellin in Padua and started working on modeling familial cardiomyopathies. 

As part of her MSCA project Nataša will focus on establishing an advanced human in vitro model of hiPSC-derived cardiac microtissues (CMTs) to understand and treat a rare cardiac disease, namely, LMNA dilated cardiomyopathy (LMNA-DCM). The project will utilize the CMTs advantages in capture post-natal and multicellular disease mechanisms to perform molecular and functional characterization of LMNA-DCM in vitro and explore the possibilities to correct the disease phenotype using novel gene editing approaches.