ERC: Gabriele Stevanato


DocProject:  HYPMET - Hyperpolarized Magnetic Resonance at the point-of-care


Gabriele Stevanato

 

ERC Grantee: Gabriele Stevanato

Department: Chemical Sciences

Total EU Contribution: Euro 1.499.969,00

Project Duration in months: 60

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Find out more: https://cordis.europa.eu/project/id/101117082

 

Gabriele Stevanato lives near S.Maria di Sala (VE) and obtained his PhD in Chemistry in 2016 from the University of Southampton (UK) under the supervision of Prof. Malcolm H. Levitt. He worked experimentally, via Nuclear Magnetic Resonance (NMR), on molecules exhibiting extended lifetimes in solution and at room temperature and co-developed a mathematical group theory for long-lived spin species in arbitrary spin systems. He was awarded the EPSRC doctoral prize fellowship allowing him to stay in UK for a bit longer.
He then moved in September 2016 to Lausanne (CH) joining the group of Prof. Lyndon Emsley shifting his interest on methods to enhance the NMR signal of species in the solid state. While there he was awarded in 2017 the Young Investigator Award at Euromar International Conference of Magnetic Resonance and in 2018 the prestigious MSCA IF from EU. He studied a new class of Gd(III) complexes to perform magic angle spinning (MAS) dynamic nuclear polarization (DNP) at 100 K improving the current state-of-the-art in signal enhancement. He investigated several nitroxide radicals for MAS DNP at very high magnetic fields (up to 21.1 T) and under fast spinning (>60 kHz). While always interested in methods boosting the NMR signal intensity, in 2020 he moved to the Max Planck Institute for Multidisciplinary Sciences (DE) joining the group of Dr. Glöggler to work with Parahydrogen Induced Polarization (PHIP) and Signal Amplification By Reversible Exchange (SABRE). There he amplified the NMR signal intensity of pyruvate and followed, in cells and in real-time, its conversion to other species. He was involved in the first project for imaging the pyruvate conversion in-vivo by PHIP.
From December 2022 is Junior PI at UniPD with HYPMAR BIO, a project on SABRE applications for real-time conversion monitoring on biologically relevant samples.