Address book

Contacts

Staff Structures

GIANFRANCO SANTOVITO

Back to the list

Position

Professore Associato

Structure

Dipartimento di Biologia - DiBio

Address

VIA U. BASSI, 58/B - PADOVA

Telephone

0498276310

E-mail

gianfranco.santovito@unipd.it

Born in Manfredonia in 1965, Gianfranco Santovito holds a degree in Biological Sciences and a PhD (magna cum laude) in Evolutionary Biology from the University of Padua. Since 2002 he has been a Lecturer of Physiology at the Department of Biology of the University of Padua, where he is an Associate Professor (qualified as a full professor from 23/07/2021). The Research Unit of Environmental Physiology and Experimental Zoology, which he coordinates, is dedicated to research activities in various areas of knowledge, which include, for example, the evolution of physiological antioxidant defence systems in various organisms such as fish, tunicates, insects, molluscs and ciliated protozoa. More recently, he has focused his interests on the physiological responses of terrestrial and aquatic animals (including humans) to global change. In addition to more purely biological research topics, in the last 10 years, he has become interested in innovative approaches to teaching biology by conducting experiments in preschool, primary and secondary schools.
He has participated and is involved in major national and international research projects, such as the LIFE-PHOENIX project funded by the European Community in 2017 (2,176 K€) on the toxicity of perfluoroalkyl substances (PFAS), the MSC-RIBES project funded by the European Community in 2019 (4,040 K€) on the anthropogenic impact on freshwater fish fauna, and the PNR-RETURN project funded by the Ministry of University and Research in 2022 (115,100 K€) on the resilience of aquatic communities to climate change.
As part of the National Antarctic Research Programme, he has participated in nine Antarctic scientific expeditions since 1998 (the last in 2022). In 2011, he was awarded the Antarctica Service Medal (approved by the US Congress) by the US National Science Foundation, in recognition of his service as a member of the 2010 US Antarctic Expedition. In 2022, he was awarded the Paul Harris Fellow, by the Rotary Foundation, for meritorious and long-standing research activities in Antarctica.
Over the years he has taught numerous degree courses, both three-year and master's degrees. Currently, at the University of Padua, he teaches the courses "Life cycles and adaptations of marine organisms" and "Ecology and physiology of global changes" for the International Master's Degree Course in Marine Biology, “Biological responses to global climate change” for the MSc course in Evolutionary Biology, of “Fundamentals and didactics of biology” for the single-cycle MSc course in Primary Education, and of “Biology, Physiology and Anatomy” for the MSc course in Biomedical Engineering. He has also supervised 11 PhD students (both Italian and foreign), 135 Master's degree students and 125 Bachelor's degree students.
Since 2008, he has served on the Editorial Board of 8 international scientific journals. In addition, he has been Reviewer of 70 international scientific journals.
He is the author of more than 310 scientific contributions published in national and international journals, books and conference proceedings. He has also published three books: "Animal Physiology" (2014), published by EdiSES, "Teaching Biology to Children" (2015), published by Carocci, and "Animal Physiology. Second Edition." (2018), published by EdiSES.

Notices

Office hours

  • Thursday from 11:00 to 13:00
    at Dipartimento di Biologia, Centro Vallisneri, Via Ugo Bassi 58B, Ala Scientifica, 6° Semipiano Sud, stanza 16.
    E' opportuno concordare un appuntamento. Sono possibili altre date ed orari oltre quelli indicati.

Teachings

Publications

Some of the most recent articles published in journals with impact factor:
1. Tolomeo A.M., Carraro A., Bakiu R., Toppo S., Garofalo F., Pellegrino D., Gerdol M., Ferro D., Place S.P., Santovito G. (2019) Molecular characterization of novel mitochondrial peroxiredoxins from the Antarctic emerald rockcod and their gene expression in response to environmental warming. Comp. Biochem. Physiol. C 255, 108580. https://doi.org/10.1016/j.cbpc.2019.108580
2. Chatzidimitriou E., Bisaccia P., Corrà F., Bonato M., Irato P., Manuto L., Toppo S., Bakiu R., Santovito G. (2020) Copper/zinc superoxide dismutase from the crocodile icefish Chionodraco hamatus: antioxidant defense at constant sub-zero temperature. Antioxidants 9, 325. https://doi.org/10.3390/antiox9040325
3. Ferro D., Bakiu R., Pucciarelli S., Miceli C., Vallesi A., Irato P., Santovito G. (2020) Molecular characterization, protein-protein interaction network, and evolution of four glutathione peroxidases from Tetrahymena thermophila. Antioxidants, 9, 949. https://doi.org/10.3390/antiox9100949
4. Bonato M., Corrà F., Bellio M., Guidolin L., Tallandini L., Irato P., Santovito G. (2020) PFAS environmental pollution and antioxidant responses: an overview of the impact on human field. Int. J. Environ. Res. Public Health, 17, 8020. https://doi.org/10.3390/ijerph17218020
5. Santovito G., Trentin E., Gobbi I., Bisaccia P., Tallandini I., Irato P. (2021) Non-enzymatic antioxidant responses of Mytilus galloprovincialis: insights into the physiological role against metal-induced oxidative stress risk. Comp. Biochem. Physiol. C, 240, 108909. https://doi.org/10.1016/j.cbpc.2020.108909
6. Motta C.M., Simoniello P., Di Lorenzo M., Migliaccio V., Panzuto R., Califano E., Santovito G. (2021) Endocrine disrupting effects of copper and cadmium in the oocytes of the Antarctic Emerald rockcod Trematomus bernacchii, Chemosphere, 268, 129282. https://doi.org/10.1016/j.chemosphere.2020.129282
7. Drago L., Peronato A., Franchi N., Ballarin L., Bakiu R., Santovito G. (2021) Stress granules in Ciona robusta: molecular evolution of TIA-1-related nucleolysin and tristetraprolin and first evidence of their gene expression in an invertebrate chordate under metal-induced stress conditions, Comp. Biochem. Physiol. C, 243, 108977. https://doi.org/10.1016/j.cbpc.2021.108977
8. Drago L., Ferro D., Bakiu R., Ballarin L., Santovito G. (2022) Typical 2-Cys Peroxiredoxins as a Defense Mechanism against Metal-Induced Oxidative Stress in the Solitary Ascidian Ciona robusta. Antioxidants, 11, 93. https://doi.org/10.3390/antiox11010093
9. Piva E., Schumann S., Dotteschini S., Brocca G., Radaelli G., Marion A., Irato P., Bertotto D., Santovito G. (2022) Antioxidant Responses Induced by PFAS Exposure in Freshwater Fish in the Veneto Region. Antioxidants, 11, 1115. https://doi.org/10.3390/antiox11061115
10. Bakiu R., Pacchini, S., Piva E., Schumann S., Tolomeo A.M., Ferro D., Irato P., Santovito G. (2022) Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni. Int. J. Mol. Sci., 23, 12799. https://doi.org/10.3390/ijms232112799E
11. Pacchini S., Piva E., Schumann S., Irato P., Pellegrino D., Santovito G. (2023) An Experimental Study on Antioxidant Enzyme Gene Expression in Trematomus newnesi (Boulenger, 1902) Experimentally Exposed to Perfluoro-octanoic Acid. Antioxidants, 12, 352. https://doi.org/10.3390/antiox12020352

Research Area

- Study of antistress (including oxidative stress) proteins in evolutionary and ecotoxicological fish and mollusks.
- Study of antistress (including oxidative stress) proteins in the solitary ascidian Ciona robusta in an evolutionary and ecotoxicological key.
- Study of the anti-stress (including oxidative stress) proteins of the ciliated protozoan Tetrahymena thermophila, used as a model organism in ecotoxicological and biomedical research.
- Study of the physiological responses of freshwater animals in relation to anthropogenic environmental stress.
- Innovative approaches to the teaching of biology in kindergarten, primary and secondary schools.

Thesis proposals

For students on master's degree courses in the biological field, theses will be placed in the following research areas:
- Study of the antioxidant system in Antarctic fish and molluscs from an evolutionary and ecotoxicological perspective.
- Study of anti-stress proteins, from an evolutionary and ecotoxicological perspective, in the solitary ascidian of the Venice Lagoon Ciona robusta (in collaboration with Prof. Ballarin of the Department of Biology of the University of Padua).
- Study of the physiological responses of freshwater animals in relation to anthropogenic environmental stress.
- Study of the antioxidant system of the ciliated protozoan Tetrahymena thermophila, also used as a model organism in ecotoxicological and biomedical research.
- Study of oxidative stress in mammalian hearts subjected to ex-situ perfusion (in collaboration with Dr. Tolomeo of the Department of Women's and Children's Health, University of Padua).

The methodologies used will range from biochemistry (UV and VIS spectrophotometric assays), to molecular biology (purification of nucleic acids; synthesis, amplification, cloning and sequencing of cDNA; semi-quantitative RT-PCR and quantitative Real Time-PCR), cytology (cell cultures of prokaryotic and eukaryotic organisms), and bioinformatics (multi-alignment of nucleotide and amino acid sequences, primers design, phylogenetic analysis by cladogram construction).

For students on the Master of Science in Primary Education course, the theses will concern educational research in the field of biology. The research activity will be conducted in a school environment where specially designed frontal and laboratory lessons will be conducted. Topics will range across all disciplines of biology, and not only with reference to the National Curriculum Directions (2012 and 2018).