Address book
Contacts
GRAZIANO MARTELLO
Position
Professore Ordinario
Structure
Address
VIALE GIUSEPPE COLOMBO, 3 - VIA UGO BASSI, 58/B - PADOVA
Telephone
0498276088
Personal Information
Name: Martello Graziano
ORCID ID: orcid.org/0000-0001-5520-085X
Education
03/2009 – PhD in Genetics and Molecular Biology of Development – Department of Histology, Microbiology and Medical Biotechnology, University of Padua
03/2005 – Five-year Degree in Medical Biotechnology, 110/110 cum laude – University of Padua
Academic Positions
03/2024 – present: Full Professor of Molecular Biology – Department of Biology – University of Padua
10/2021 – 02/2024: Associate Professor of Molecular Biology – Department of Biology – University of Padua
08/2017 – 09/2021: Associate Professor in Histology and Embryology – Department of Molecular Medicine – University of Padua
03/2014 – 12/2019: DTI Telethon Scientist
03/2014 – 07/2017: Fixed-term Researcher in Molecular Biology
04/2010 – 02/2014: Research Associate at the WT-MRC Stem Cell Institute – University of Cambridge, UK
01/2009 – 03/2010: Postdoctoral Fellow at the Department of Histology, Microbiology and Medical Biotechnology, University of Padua
Teaching Activity
2022 – present: Course in Developmental Molecular Biology, Bachelor's Degree in Molecular Biology, University of Padua
2021 – 2023: Course in Molecular Biology and Genetic Engineering, Bachelor's Degree in Biotechnology, University of Padua
2019 – 2022: Course in Functionality, Physiology and Architecture of Cells, Degree in Medicine and Surgery, University of Padua
2018 – 2021: Course in Histology, Degree in Medicine and Surgery, University of Padua
2015 – 2022: Course in Stem Cell Biology and Developmental Molecular Biology, Degree in Medicine and Surgery, University of Padua
2014 – 2018: Course in Molecular Biology, Degree in Medicine and Surgery, University of Padua
Institutional Roles
2022 – present: Member of the Doctoral School in Biosciences, University of Padua
2018 – present: Member of the Scientific Board of the Italian Society of Biophysics and Molecular Biology (SIBBM)
2017 – present: Member of the Quality Assurance Committee for the Third Mission, University of Padua
2016 – present: Member of the International Society for Stem Cell Research (ISSCR)
2014 – 2021: Member of the Doctoral School in Molecular Biology, University of Padua
2013 – present: PhD student supervisor at the University of Cambridge, UK
Awards and Funding
2010 – “Cecilia Cioffrese” Award from the Carlo Erba Foundation
2012 – “Young Venetian Excellence Award 2012” in the field of Life Sciences
2013 – Armenise-Harvard Career Development Award – Armenise-Harvard Foundation
2013 – Telethon DTI Career Development Award
2016 – European Research Council (ERC) Starting Grant – Project “MetEpiStem”
2021 – Start Cup Veneto – First Prize, Best Startup Idea
2024 – Winner with the startup DNASwitch of the "BOOSTER FOR LIFE SCIENCE – TRL ADVANCEMENT"
2024 – Winner with the startup DNASwitch in the I-Tech Innovation Program 2023–2024 (Life Sciences sector)
Since 2013, reviewer of scientific articles for international journals including Development, Nature Communications, Stem Cell, Nature Cell Biology, The EMBO Journal, Cell Stem Cell, and Nature.
Notices
Pubblicazioni
Yordanov B, Dunn SJ, Kugler H, Smith A, Martello G, Emmott S. A Method to
Identify and Analyze Biological Programs through Automated Reasoning. NPJ Syst
Biol Appl. 2016 Jul 7;2. pii: 16010. doi: 10.1038/npjsba.2016.10.
Carbognin E, Betto RM, Soriano ME, Smith AG, Martello G. Stat3 promotes
mitochondrial transcription and oxidative respiration during maintenance and
induction of naive pluripotency. EMBO J. 2016 Mar 15;35(6):618-34. doi:
10.15252/embj.201592629.
Montagner M, Martello G, Piccolo S. Monitoring Smad Activity In Vivo Using the
Xenopus Model System. Methods Mol Biol. 2016;1344:245-59. doi:
10.1007/978-1-4939-2966-5_15.
Martello G, Smith A. The nature of embryonic stem cells. Annu Rev Cell Dev
Biol. 2014;30:647-75. doi: 10.1146/annurev-cellbio-100913-013116. Review.
Stuart HT, van Oosten AL, Radzisheuskaya A, Martello G, Miller A, Dietmann S,
Nichols J, Silva JC. NANOG amplifies STAT3 activation and they synergistically
induce the naive pluripotent program. Curr Biol. 2014 Feb 3;24(3):340-6. doi:
10.1016/j.cub.2013.12.040.
Leitch HG, Nichols J, Humphreys P, Mulas C, Martello G, Lee C, Jones K, Surani
MA, Smith A. Rebuilding pluripotency from primordial germ cells. Stem Cell
Reports. 2013 Jun 4;1(1):66-78. doi: 10.1016/j.stemcr.2013.03.004.
Martello G, Bertone P, Smith A. Identification of the missing pluripotency
mediator downstream of leukaemia inhibitory factor. EMBO J. 2013 Oct
2;32(19):2561-74. doi: 10.1038/emboj.2013.177.
Martello G, Sugimoto T, Diamanti E, Joshi A, Hannah R, Ohtsuka S, Göttgens B,
Niwa H, Smith A. Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating
embryonic stem cell self-renewal. Cell Stem Cell. 2012 Oct 5;11(4):491-504. doi:
10.1016/j.stem.2012.06.008.
Inui M, Montagner M, Ben-Zvi D, Martello G, Soligo S, Manfrin A, Aragona M,
Enzo E, Zacchigna L, Zanconato F, Azzolin L, Dupont S, Cordenonsi M, Piccolo S.
Self-regulation of the head-inducing properties of the Spemann organizer. Proc
Natl Acad Sci U S A. 2012 Sep 18;109(38):15354-9.
Inui M, Manfrin A, Mamidi A, Martello G, Morsut L, Soligo S, Enzo E, Moro S,
Polo S, Dupont S, Cordenonsi M, Piccolo S. USP15 is a deubiquitylating enzyme for
receptor-activated SMADs. Nat Cell Biol. 2011 Sep 25;13(11):1368-75. doi:
10.1038/ncb2346.
Martello G, Rosato A, Ferrari F, Manfrin A, Cordenonsi M, Dupont S, Enzo E,
Guzzardo V, Rondina M, Spruce T, Parenti AR, Daidone MG, Bicciato S, Piccolo S. A
MicroRNA targeting dicer for metastasis control. Cell. 2010 Jun
25;141(7):1195-207. doi: 10.1016/j.cell.2010.05.017.
Inui M, Martello G, Piccolo S. MicroRNA control of signal transduction. Nat
Rev Mol Cell Biol. 2010 Apr;11(4):252-63. doi: 10.1038/nrm2868.
Dupont S, Mamidi A, Cordenonsi M, Montagner M, Zacchigna L, Adorno M,
Martello G, Stinchfield MJ, Soligo S, Morsut L, Inui M, Moro S, Modena N,
Argenton F, Newfeld SJ, Piccolo S. FAM/USP9x, a deubiquitinating enzyme essential
for TGFbeta signaling, controls Smad4 monoubiquitination. Cell. 2009 Jan
9;136(1):123-35. doi: 10.1016/j.cell.2008.10.051.
Martello G, Zacchigna L, Inui M, Montagner M, Adorno M, Mamidi A, Morsut L,
Soligo S, Tran U, Dupont S, Cordenonsi M, Wessely O, Piccolo S. MicroRNA control
of Nodal signalling. Nature. 2007 Sep 13;449(7159):183-8.
Cordenonsi M et al - Integration of TGF-b and Ras/MAPK signaling through p53 phosphorylation. Science. 2007 Feb 9;315(5813)
