The research activity concerns the study of neurodegenerative diseases, such as Parkinson's disease, amyotrophic lateral sclerosis and rare forms of neurodegeneration associated with iron accumulation using both cellular and Drosophila pathological models

TECHNIQUES
In our laboratory, we used the main biochemical (western blots, enzymatic assays, etc.) and imaging (epifluorescence, confocal microscopy, etc.) techniques.
Behavioral tests are also carried out on flies

In the lab, we are interested in understanding the molecular determinants underlying the pathogenesis of different neurodegenerative disorders. By exploiting both cellular and Drosophila melanogaster models of the disorders, we investigate the contribution of neurons and glial cells to the pathologies.
Currently, we have open positions on the following topics:

1) Analysis of the involvement of ferroptosis in a Drosophila melanogaster model of amyotrophic lateral sclerosis

2) Assessment of the physiological role of the protein C19orf12 involved in a genetic form of neurodegeneration with brain iron accumulation