Informazioni, prenotazioni, acquisti - Sala Giganti - informazioni e tariffe

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  • Centro Prenotazioni: 049 827 3939 - tour@unipd.it (tutti i giorni, ore 9-17)
  • Biglietteria di Palazzo del Bo (situata nel corridoio di passaggio tra i due Cortili):
    - dal lunedì al venerdì, ore 10-18
    - sabato, domenica e festivi, ore 9-18

Le prenotazioni già pagate e i biglietti già acquistati non possono essere modificati, annullati o rimborsati

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  • Centro Prenotazioni: 049 827 3939 - tour@unipd.it (tutti i giorni, ore 9-17)
  • Biglietteria di Palazzo del Bo (situata nel corridoio di passaggio tra i due Cortili):
    - dal lunedì al venerdì, ore 10-18
    - sabato, domenica e festivi, ore 9-18

Le prenotazioni già pagate e i biglietti già acquistati non possono essere modificati, annullati o rimborsati

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Informazioni, prenotazioni, acquisti

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Informazioni, prenotazioni, acquisti

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Informazioni, prenotazioni, acquisti

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Informazioni, prenotazioni, acquisti

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Informazioni, prenotazioni, acquisti

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  • Centro Prenotazioni: 049 827 3939 - tour@unipd.it (tutti i giorni, ore 9-17)
  • Biglietteria di Palazzo del Bo (situata nel corridoio di passaggio tra i due Cortili):
    - dal lunedì al venerdì, ore 10-18
    - sabato, domenica e festivi, ore 9-18

Le prenotazioni già pagate e i biglietti già acquistati non possono essere modificati, annullati o rimborsati

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  • Centro Prenotazioni: 049 827 3939 - tour@unipd.it (tutti i giorni, ore 9-17)
  • Biglietteria di Palazzo del Bo (situata nel corridoio di passaggio tra i due Cortili):
    - dal lunedì al venerdì, ore 10-18
    - sabato, domenica e festivi, ore 9-18

Le prenotazioni già pagate e i biglietti già acquistati non possono essere modificati, annullati o rimborsati

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Informazioni, prenotazioni, acquisti

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Informazioni, prenotazioni, acquisti

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  • Centro Prenotazioni: 049 827 3939 - tour@unipd.it (tutti i giorni, ore 9-17)
  • Biglietteria di Palazzo del Bo (situata nel corridoio di passaggio tra i due Cortili):
    - dal lunedì al venerdì, ore 10-18
    - sabato, domenica e festivi, ore 9-18

Le prenotazioni già pagate e i biglietti già acquistati non possono essere modificati, annullati o rimborsati

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  • Centro Prenotazioni: 049 827 3939 - tour@unipd.it (tutti i giorni, ore 9-17)
  • Biglietteria di Palazzo del Bo (situata nel corridoio di passaggio tra i due Cortili):
    - dal lunedì al venerdì, ore 10-18
    - sabato, domenica e festivi, ore 9-18

Le prenotazioni già pagate e i biglietti già acquistati non possono essere modificati, annullati o rimborsati

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  • Centro Prenotazioni: 049 827 3939 - tour@unipd.it (tutti i giorni, ore 9-17)
  • Biglietteria di Palazzo del Bo (situata nel corridoio di passaggio tra i due Cortili):
    - dal lunedì al venerdì, ore 10-18
    - sabato, domenica e festivi, ore 9-18

Le prenotazioni già pagate e i biglietti già acquistati non possono essere modificati, annullati o rimborsati

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2023N54 - Esito procedura di Mobilità Obbligatoria ex art. 34-bis del D.Lgs. 165/2001 s.m.i. (pubblicato all'Albo Ufficiale di Ateneo in data 03/11/2023)

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2023N53 - Esito procedura di Mobilità Obbligatoria ex art. 34-bis del D.Lgs. 165/2001 s.m.i. (pubblicato all'Albo Ufficiale di Ateneo in data 03/11/2023)

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PhD Welcome Day

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

Registration

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

Registration

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

Registration

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

Registration

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

Registration

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

Registration

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

Registration

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

Registration

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

Registration

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

Registration

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

Registration

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The University of Padua wants to give to the new PhD students (39th series) a warm welcome, organizing the PhD Welcome Day on November 18, 2023, h. 10-12.30, in Complesso Beato Pellegrino.

During the meeting PhD students are introduced to the University and the city of Padova and are provided with all the information needed to ensure a great and fruitful stay at Unipd. Specific information is provided about PhD opportunities, events, co-tutelage agreement, scholarship increase.

Registration

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Advanced assisted reproduction technologies against the imminent extinction of most rhino species

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As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

The application of aART is the only option to create offspring for the northern white rhinoceros, a subspecies with only two individuals known to be alive – two females that cannot become pregnant anymore to carry out their own embryos.

The BioRescue project, led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), develops and pioneers these technologies to enhance the breeding success of southern white rhinos in human care and to save the northern white rhino from extinction.

The consortium takes animal safety and welfare, quality control and ethical risk assessment seriously and constantly evaluates its new scientific and veterinary procedures. BioRescue has performed 65 aART procedures from 2015 to 2022 and now published an evaluation of these data in the scientific journal “Reproduction”.

The international research team, including those from the University of Padua, analysed animal health and health effects of the procedures, age and seasonality, subspecies and origins of individuals, hormonal status and cyclicity as well as the effects of the stimulation protocol in relation to OPU and IVF success rates with 20 southern and two northern white rhino females.  

Their most important findings are:

  • The set of procedures proved to be a guarantee for successful production of white rhino embryos
  • Repeated OPUs yield no indications of adverse effects on general and reproductive health, with no sign of detrimental effects or risks even after ten procedures performed at three-month intervals
  • Clear indications of health benefits to individuals exposed to OPUs
  • Ensuring that OPU procedures do not hamper natural reproduction
  • Noting that the age of the oocyte donor was key for IVF success
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As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

The application of aART is the only option to create offspring for the northern white rhinoceros, a subspecies with only two individuals known to be alive – two females that cannot become pregnant anymore to carry out their own embryos.

The BioRescue project, led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), develops and pioneers these technologies to enhance the breeding success of southern white rhinos in human care and to save the northern white rhino from extinction.

The consortium takes animal safety and welfare, quality control and ethical risk assessment seriously and constantly evaluates its new scientific and veterinary procedures. BioRescue has performed 65 aART procedures from 2015 to 2022 and now published an evaluation of these data in the scientific journal “Reproduction”.

The international research team, including those from the University of Padua, analysed animal health and health effects of the procedures, age and seasonality, subspecies and origins of individuals, hormonal status and cyclicity as well as the effects of the stimulation protocol in relation to OPU and IVF success rates with 20 southern and two northern white rhino females.  

Their most important findings are:

  • The set of procedures proved to be a guarantee for successful production of white rhino embryos
  • Repeated OPUs yield no indications of adverse effects on general and reproductive health, with no sign of detrimental effects or risks even after ten procedures performed at three-month intervals
  • Clear indications of health benefits to individuals exposed to OPUs
  • Ensuring that OPU procedures do not hamper natural reproduction
  • Noting that the age of the oocyte donor was key for IVF success
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As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

The application of aART is the only option to create offspring for the northern white rhinoceros, a subspecies with only two individuals known to be alive – two females that cannot become pregnant anymore to carry out their own embryos.

The BioRescue project, led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), develops and pioneers these technologies to enhance the breeding success of southern white rhinos in human care and to save the northern white rhino from extinction.

The consortium takes animal safety and welfare, quality control and ethical risk assessment seriously and constantly evaluates its new scientific and veterinary procedures. BioRescue has performed 65 aART procedures from 2015 to 2022 and now published an evaluation of these data in the scientific journal “Reproduction”.

The international research team, including those from the University of Padua, analysed animal health and health effects of the procedures, age and seasonality, subspecies and origins of individuals, hormonal status and cyclicity as well as the effects of the stimulation protocol in relation to OPU and IVF success rates with 20 southern and two northern white rhino females.  

Their most important findings are:

  • The set of procedures proved to be a guarantee for successful production of white rhino embryos
  • Repeated OPUs yield no indications of adverse effects on general and reproductive health, with no sign of detrimental effects or risks even after ten procedures performed at three-month intervals
  • Clear indications of health benefits to individuals exposed to OPUs
  • Ensuring that OPU procedures do not hamper natural reproduction
  • Noting that the age of the oocyte donor was key for IVF success
[summary] => [format] => 2 [safe_value] =>

As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

The application of aART is the only option to create offspring for the northern white rhinoceros, a subspecies with only two individuals known to be alive – two females that cannot become pregnant anymore to carry out their own embryos.

The BioRescue project, led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), develops and pioneers these technologies to enhance the breeding success of southern white rhinos in human care and to save the northern white rhino from extinction.

The consortium takes animal safety and welfare, quality control and ethical risk assessment seriously and constantly evaluates its new scientific and veterinary procedures. BioRescue has performed 65 aART procedures from 2015 to 2022 and now published an evaluation of these data in the scientific journal “Reproduction”.

The international research team, including those from the University of Padua, analysed animal health and health effects of the procedures, age and seasonality, subspecies and origins of individuals, hormonal status and cyclicity as well as the effects of the stimulation protocol in relation to OPU and IVF success rates with 20 southern and two northern white rhino females.  

Their most important findings are:

  • The set of procedures proved to be a guarantee for successful production of white rhino embryos
  • Repeated OPUs yield no indications of adverse effects on general and reproductive health, with no sign of detrimental effects or risks even after ten procedures performed at three-month intervals
  • Clear indications of health benefits to individuals exposed to OPUs
  • Ensuring that OPU procedures do not hamper natural reproduction
  • Noting that the age of the oocyte donor was key for IVF success
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As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

The application of aART is the only option to create offspring for the northern white rhinoceros, a subspecies with only two individuals known to be alive – two females that cannot become pregnant anymore to carry out their own embryos.

The BioRescue project, led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), develops and pioneers these technologies to enhance the breeding success of southern white rhinos in human care and to save the northern white rhino from extinction.

The consortium takes animal safety and welfare, quality control and ethical risk assessment seriously and constantly evaluates its new scientific and veterinary procedures. BioRescue has performed 65 aART procedures from 2015 to 2022 and now published an evaluation of these data in the scientific journal “Reproduction”.

The international research team, including those from the University of Padua, analysed animal health and health effects of the procedures, age and seasonality, subspecies and origins of individuals, hormonal status and cyclicity as well as the effects of the stimulation protocol in relation to OPU and IVF success rates with 20 southern and two northern white rhino females.  

Their most important findings are:

  • The set of procedures proved to be a guarantee for successful production of white rhino embryos
  • Repeated OPUs yield no indications of adverse effects on general and reproductive health, with no sign of detrimental effects or risks even after ten procedures performed at three-month intervals
  • Clear indications of health benefits to individuals exposed to OPUs
  • Ensuring that OPU procedures do not hamper natural reproduction
  • Noting that the age of the oocyte donor was key for IVF success
[summary] => [format] => 2 [safe_value] =>

As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

The application of aART is the only option to create offspring for the northern white rhinoceros, a subspecies with only two individuals known to be alive – two females that cannot become pregnant anymore to carry out their own embryos.

The BioRescue project, led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), develops and pioneers these technologies to enhance the breeding success of southern white rhinos in human care and to save the northern white rhino from extinction.

The consortium takes animal safety and welfare, quality control and ethical risk assessment seriously and constantly evaluates its new scientific and veterinary procedures. BioRescue has performed 65 aART procedures from 2015 to 2022 and now published an evaluation of these data in the scientific journal “Reproduction”.

The international research team, including those from the University of Padua, analysed animal health and health effects of the procedures, age and seasonality, subspecies and origins of individuals, hormonal status and cyclicity as well as the effects of the stimulation protocol in relation to OPU and IVF success rates with 20 southern and two northern white rhino females.  

Their most important findings are:

  • The set of procedures proved to be a guarantee for successful production of white rhino embryos
  • Repeated OPUs yield no indications of adverse effects on general and reproductive health, with no sign of detrimental effects or risks even after ten procedures performed at three-month intervals
  • Clear indications of health benefits to individuals exposed to OPUs
  • Ensuring that OPU procedures do not hamper natural reproduction
  • Noting that the age of the oocyte donor was key for IVF success
[safe_summary] => ) ) [#formatter] => text_summary_or_trimmed [0] => Array ( [#markup] =>

As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

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As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

The application of aART is the only option to create offspring for the northern white rhinoceros, a subspecies with only two individuals known to be alive – two females that cannot become pregnant anymore to carry out their own embryos.

The BioRescue project, led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), develops and pioneers these technologies to enhance the breeding success of southern white rhinos in human care and to save the northern white rhino from extinction.

The consortium takes animal safety and welfare, quality control and ethical risk assessment seriously and constantly evaluates its new scientific and veterinary procedures. BioRescue has performed 65 aART procedures from 2015 to 2022 and now published an evaluation of these data in the scientific journal “Reproduction”.

The international research team, including those from the University of Padua, analysed animal health and health effects of the procedures, age and seasonality, subspecies and origins of individuals, hormonal status and cyclicity as well as the effects of the stimulation protocol in relation to OPU and IVF success rates with 20 southern and two northern white rhino females.  

Their most important findings are:

  • The set of procedures proved to be a guarantee for successful production of white rhino embryos
  • Repeated OPUs yield no indications of adverse effects on general and reproductive health, with no sign of detrimental effects or risks even after ten procedures performed at three-month intervals
  • Clear indications of health benefits to individuals exposed to OPUs
  • Ensuring that OPU procedures do not hamper natural reproduction
  • Noting that the age of the oocyte donor was key for IVF success
[summary] => [format] => 2 [safe_value] =>

As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

The application of aART is the only option to create offspring for the northern white rhinoceros, a subspecies with only two individuals known to be alive – two females that cannot become pregnant anymore to carry out their own embryos.

The BioRescue project, led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), develops and pioneers these technologies to enhance the breeding success of southern white rhinos in human care and to save the northern white rhino from extinction.

The consortium takes animal safety and welfare, quality control and ethical risk assessment seriously and constantly evaluates its new scientific and veterinary procedures. BioRescue has performed 65 aART procedures from 2015 to 2022 and now published an evaluation of these data in the scientific journal “Reproduction”.

The international research team, including those from the University of Padua, analysed animal health and health effects of the procedures, age and seasonality, subspecies and origins of individuals, hormonal status and cyclicity as well as the effects of the stimulation protocol in relation to OPU and IVF success rates with 20 southern and two northern white rhino females.  

Their most important findings are:

  • The set of procedures proved to be a guarantee for successful production of white rhino embryos
  • Repeated OPUs yield no indications of adverse effects on general and reproductive health, with no sign of detrimental effects or risks even after ten procedures performed at three-month intervals
  • Clear indications of health benefits to individuals exposed to OPUs
  • Ensuring that OPU procedures do not hamper natural reproduction
  • Noting that the age of the oocyte donor was key for IVF success
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As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

The application of aART is the only option to create offspring for the northern white rhinoceros, a subspecies with only two individuals known to be alive – two females that cannot become pregnant anymore to carry out their own embryos.

The BioRescue project, led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), develops and pioneers these technologies to enhance the breeding success of southern white rhinos in human care and to save the northern white rhino from extinction.

The consortium takes animal safety and welfare, quality control and ethical risk assessment seriously and constantly evaluates its new scientific and veterinary procedures. BioRescue has performed 65 aART procedures from 2015 to 2022 and now published an evaluation of these data in the scientific journal “Reproduction”.

The international research team, including those from the University of Padua, analysed animal health and health effects of the procedures, age and seasonality, subspecies and origins of individuals, hormonal status and cyclicity as well as the effects of the stimulation protocol in relation to OPU and IVF success rates with 20 southern and two northern white rhino females.  

Their most important findings are:

  • The set of procedures proved to be a guarantee for successful production of white rhino embryos
  • Repeated OPUs yield no indications of adverse effects on general and reproductive health, with no sign of detrimental effects or risks even after ten procedures performed at three-month intervals
  • Clear indications of health benefits to individuals exposed to OPUs
  • Ensuring that OPU procedures do not hamper natural reproduction
  • Noting that the age of the oocyte donor was key for IVF success
[summary] => [format] => 2 [safe_value] =>

As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

The application of aART is the only option to create offspring for the northern white rhinoceros, a subspecies with only two individuals known to be alive – two females that cannot become pregnant anymore to carry out their own embryos.

The BioRescue project, led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), develops and pioneers these technologies to enhance the breeding success of southern white rhinos in human care and to save the northern white rhino from extinction.

The consortium takes animal safety and welfare, quality control and ethical risk assessment seriously and constantly evaluates its new scientific and veterinary procedures. BioRescue has performed 65 aART procedures from 2015 to 2022 and now published an evaluation of these data in the scientific journal “Reproduction”.

The international research team, including those from the University of Padua, analysed animal health and health effects of the procedures, age and seasonality, subspecies and origins of individuals, hormonal status and cyclicity as well as the effects of the stimulation protocol in relation to OPU and IVF success rates with 20 southern and two northern white rhino females.  

Their most important findings are:

  • The set of procedures proved to be a guarantee for successful production of white rhino embryos
  • Repeated OPUs yield no indications of adverse effects on general and reproductive health, with no sign of detrimental effects or risks even after ten procedures performed at three-month intervals
  • Clear indications of health benefits to individuals exposed to OPUs
  • Ensuring that OPU procedures do not hamper natural reproduction
  • Noting that the age of the oocyte donor was key for IVF success
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As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

The application of aART is the only option to create offspring for the northern white rhinoceros, a subspecies with only two individuals known to be alive – two females that cannot become pregnant anymore to carry out their own embryos.

The BioRescue project, led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), develops and pioneers these technologies to enhance the breeding success of southern white rhinos in human care and to save the northern white rhino from extinction.

The consortium takes animal safety and welfare, quality control and ethical risk assessment seriously and constantly evaluates its new scientific and veterinary procedures. BioRescue has performed 65 aART procedures from 2015 to 2022 and now published an evaluation of these data in the scientific journal “Reproduction”.

The international research team, including those from the University of Padua, analysed animal health and health effects of the procedures, age and seasonality, subspecies and origins of individuals, hormonal status and cyclicity as well as the effects of the stimulation protocol in relation to OPU and IVF success rates with 20 southern and two northern white rhino females.  

Their most important findings are:

  • The set of procedures proved to be a guarantee for successful production of white rhino embryos
  • Repeated OPUs yield no indications of adverse effects on general and reproductive health, with no sign of detrimental effects or risks even after ten procedures performed at three-month intervals
  • Clear indications of health benefits to individuals exposed to OPUs
  • Ensuring that OPU procedures do not hamper natural reproduction
  • Noting that the age of the oocyte donor was key for IVF success
[summary] => [format] => 2 [safe_value] =>

As most rhino species and subspecies face impairment of natural reproduction and imminent extinction, new approaches to their conservation are vital. The most promising new approach is the application of advanced assisted reproduction technologies (aART) such as ovum pick-up (OPU) – the retrieval of immature egg cells (oocytes) from ovaries – and in-vitro fertilisation (IVF). These technologies enable the creation of embryos in the lab and transfer them into surrogate mothers to carry gestation to term.

The application of aART is the only option to create offspring for the northern white rhinoceros, a subspecies with only two individuals known to be alive – two females that cannot become pregnant anymore to carry out their own embryos.

The BioRescue project, led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), develops and pioneers these technologies to enhance the breeding success of southern white rhinos in human care and to save the northern white rhino from extinction.

The consortium takes animal safety and welfare, quality control and ethical risk assessment seriously and constantly evaluates its new scientific and veterinary procedures. BioRescue has performed 65 aART procedures from 2015 to 2022 and now published an evaluation of these data in the scientific journal “Reproduction”.

The international research team, including those from the University of Padua, analysed animal health and health effects of the procedures, age and seasonality, subspecies and origins of individuals, hormonal status and cyclicity as well as the effects of the stimulation protocol in relation to OPU and IVF success rates with 20 southern and two northern white rhino females.  

Their most important findings are:

  • The set of procedures proved to be a guarantee for successful production of white rhino embryos
  • Repeated OPUs yield no indications of adverse effects on general and reproductive health, with no sign of detrimental effects or risks even after ten procedures performed at three-month intervals
  • Clear indications of health benefits to individuals exposed to OPUs
  • Ensuring that OPU procedures do not hamper natural reproduction
  • Noting that the age of the oocyte donor was key for IVF success
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corso AF 23/24 - Riconoscimento precoce e interventi multidisciplinari nei disturbi della nutrizione e dell'alimentazione

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Scadenza preiscrizioni: 13 dicembre 2024, ore 12.30

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Avviso di selezione - Riconoscimento precoce e interventi multidisciplinari nei disturbi della nutrizione e dell'alimentazione

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Investigating the impact of dredged sediments on the microbial communities of Manila clams

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

In the study, Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition researchers exposed clams to sediment samples collected from different sites within one of the Venice lagoon navigable canals close to the industrial area of Porto Marghera, as a means to define the molecular mechanisms behind sediment toxicity. Results reveal transcriptional and microbial changes of Manila clams after exposure to sediments. The work underlines how the correct management in the reuse of dredged sediments is crucial for the conservation of this species and possibly for other organisms inhabiting the Venice lagoon.

Thanks to the scientific activity performed in the Research Programme Venezia2021, coordinated by CORILA, with the contribution of the Provveditorato for the Public Works of Veneto, Trentino Alto Adige and Friuli Venezia Giulia, this study defined the Manila clam molecular mechanisms involved in the response to complex chemical mixtures characteristic of urban and industrial areas.

The management of dredged sediments in ports and lagoons must aim at avoiding potential impacts on marine ecosystems. Therefore, researchers must investigate the possible effects of complex mixtures of chemical contaminants present in sediments on animal species residing in lagoons and coastal areas.

Last author, Tomaso Patarnello explains, “Organisms exposed to polluted sediments, where PCBs concentrations were up to 120 times higher than in control areas, underwent significant alterations in the expression of genes involved in the response to complex chemical mixtures characteristic of urban and industrial areas. In particular, at the transcriptional level, we found a persistent activation of the mTORC1 signalling pathway, which is central in the coordination of cellular responses to chemical stress. We also observed the overrepresentation of potential pathogens and the upregulation of several pathways involved in the immune response of clams exposed to sediments from specific sites.

Corresponding author, Massimo Milan, concludes, “The results obtained highlight how the correct management of dredged sediments is essential for the conservation of this species and, more generally, how investigations conducted at a molecular level can also contribute to understanding the complexity of potential adverse effects on organisms inhabiting the Venice lagoon due to exposure to contaminated sediments.”

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

In the study, Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition researchers exposed clams to sediment samples collected from different sites within one of the Venice lagoon navigable canals close to the industrial area of Porto Marghera, as a means to define the molecular mechanisms behind sediment toxicity. Results reveal transcriptional and microbial changes of Manila clams after exposure to sediments. The work underlines how the correct management in the reuse of dredged sediments is crucial for the conservation of this species and possibly for other organisms inhabiting the Venice lagoon.

Thanks to the scientific activity performed in the Research Programme Venezia2021, coordinated by CORILA, with the contribution of the Provveditorato for the Public Works of Veneto, Trentino Alto Adige and Friuli Venezia Giulia, this study defined the Manila clam molecular mechanisms involved in the response to complex chemical mixtures characteristic of urban and industrial areas.

The management of dredged sediments in ports and lagoons must aim at avoiding potential impacts on marine ecosystems. Therefore, researchers must investigate the possible effects of complex mixtures of chemical contaminants present in sediments on animal species residing in lagoons and coastal areas.

Last author, Tomaso Patarnello explains, “Organisms exposed to polluted sediments, where PCBs concentrations were up to 120 times higher than in control areas, underwent significant alterations in the expression of genes involved in the response to complex chemical mixtures characteristic of urban and industrial areas. In particular, at the transcriptional level, we found a persistent activation of the mTORC1 signalling pathway, which is central in the coordination of cellular responses to chemical stress. We also observed the overrepresentation of potential pathogens and the upregulation of several pathways involved in the immune response of clams exposed to sediments from specific sites.

Corresponding author, Massimo Milan, concludes, “The results obtained highlight how the correct management of dredged sediments is essential for the conservation of this species and, more generally, how investigations conducted at a molecular level can also contribute to understanding the complexity of potential adverse effects on organisms inhabiting the Venice lagoon due to exposure to contaminated sediments.”

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

In the study, Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition researchers exposed clams to sediment samples collected from different sites within one of the Venice lagoon navigable canals close to the industrial area of Porto Marghera, as a means to define the molecular mechanisms behind sediment toxicity. Results reveal transcriptional and microbial changes of Manila clams after exposure to sediments. The work underlines how the correct management in the reuse of dredged sediments is crucial for the conservation of this species and possibly for other organisms inhabiting the Venice lagoon.

Thanks to the scientific activity performed in the Research Programme Venezia2021, coordinated by CORILA, with the contribution of the Provveditorato for the Public Works of Veneto, Trentino Alto Adige and Friuli Venezia Giulia, this study defined the Manila clam molecular mechanisms involved in the response to complex chemical mixtures characteristic of urban and industrial areas.

The management of dredged sediments in ports and lagoons must aim at avoiding potential impacts on marine ecosystems. Therefore, researchers must investigate the possible effects of complex mixtures of chemical contaminants present in sediments on animal species residing in lagoons and coastal areas.

Last author, Tomaso Patarnello explains, “Organisms exposed to polluted sediments, where PCBs concentrations were up to 120 times higher than in control areas, underwent significant alterations in the expression of genes involved in the response to complex chemical mixtures characteristic of urban and industrial areas. In particular, at the transcriptional level, we found a persistent activation of the mTORC1 signalling pathway, which is central in the coordination of cellular responses to chemical stress. We also observed the overrepresentation of potential pathogens and the upregulation of several pathways involved in the immune response of clams exposed to sediments from specific sites.

Corresponding author, Massimo Milan, concludes, “The results obtained highlight how the correct management of dredged sediments is essential for the conservation of this species and, more generally, how investigations conducted at a molecular level can also contribute to understanding the complexity of potential adverse effects on organisms inhabiting the Venice lagoon due to exposure to contaminated sediments.”

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

In the study, Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition researchers exposed clams to sediment samples collected from different sites within one of the Venice lagoon navigable canals close to the industrial area of Porto Marghera, as a means to define the molecular mechanisms behind sediment toxicity. Results reveal transcriptional and microbial changes of Manila clams after exposure to sediments. The work underlines how the correct management in the reuse of dredged sediments is crucial for the conservation of this species and possibly for other organisms inhabiting the Venice lagoon.

Thanks to the scientific activity performed in the Research Programme Venezia2021, coordinated by CORILA, with the contribution of the Provveditorato for the Public Works of Veneto, Trentino Alto Adige and Friuli Venezia Giulia, this study defined the Manila clam molecular mechanisms involved in the response to complex chemical mixtures characteristic of urban and industrial areas.

The management of dredged sediments in ports and lagoons must aim at avoiding potential impacts on marine ecosystems. Therefore, researchers must investigate the possible effects of complex mixtures of chemical contaminants present in sediments on animal species residing in lagoons and coastal areas.

Last author, Tomaso Patarnello explains, “Organisms exposed to polluted sediments, where PCBs concentrations were up to 120 times higher than in control areas, underwent significant alterations in the expression of genes involved in the response to complex chemical mixtures characteristic of urban and industrial areas. In particular, at the transcriptional level, we found a persistent activation of the mTORC1 signalling pathway, which is central in the coordination of cellular responses to chemical stress. We also observed the overrepresentation of potential pathogens and the upregulation of several pathways involved in the immune response of clams exposed to sediments from specific sites.

Corresponding author, Massimo Milan, concludes, “The results obtained highlight how the correct management of dredged sediments is essential for the conservation of this species and, more generally, how investigations conducted at a molecular level can also contribute to understanding the complexity of potential adverse effects on organisms inhabiting the Venice lagoon due to exposure to contaminated sediments.”

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

In the study, Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition researchers exposed clams to sediment samples collected from different sites within one of the Venice lagoon navigable canals close to the industrial area of Porto Marghera, as a means to define the molecular mechanisms behind sediment toxicity. Results reveal transcriptional and microbial changes of Manila clams after exposure to sediments. The work underlines how the correct management in the reuse of dredged sediments is crucial for the conservation of this species and possibly for other organisms inhabiting the Venice lagoon.

Thanks to the scientific activity performed in the Research Programme Venezia2021, coordinated by CORILA, with the contribution of the Provveditorato for the Public Works of Veneto, Trentino Alto Adige and Friuli Venezia Giulia, this study defined the Manila clam molecular mechanisms involved in the response to complex chemical mixtures characteristic of urban and industrial areas.

The management of dredged sediments in ports and lagoons must aim at avoiding potential impacts on marine ecosystems. Therefore, researchers must investigate the possible effects of complex mixtures of chemical contaminants present in sediments on animal species residing in lagoons and coastal areas.

Last author, Tomaso Patarnello explains, “Organisms exposed to polluted sediments, where PCBs concentrations were up to 120 times higher than in control areas, underwent significant alterations in the expression of genes involved in the response to complex chemical mixtures characteristic of urban and industrial areas. In particular, at the transcriptional level, we found a persistent activation of the mTORC1 signalling pathway, which is central in the coordination of cellular responses to chemical stress. We also observed the overrepresentation of potential pathogens and the upregulation of several pathways involved in the immune response of clams exposed to sediments from specific sites.

Corresponding author, Massimo Milan, concludes, “The results obtained highlight how the correct management of dredged sediments is essential for the conservation of this species and, more generally, how investigations conducted at a molecular level can also contribute to understanding the complexity of potential adverse effects on organisms inhabiting the Venice lagoon due to exposure to contaminated sediments.”

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

In the study, Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition researchers exposed clams to sediment samples collected from different sites within one of the Venice lagoon navigable canals close to the industrial area of Porto Marghera, as a means to define the molecular mechanisms behind sediment toxicity. Results reveal transcriptional and microbial changes of Manila clams after exposure to sediments. The work underlines how the correct management in the reuse of dredged sediments is crucial for the conservation of this species and possibly for other organisms inhabiting the Venice lagoon.

Thanks to the scientific activity performed in the Research Programme Venezia2021, coordinated by CORILA, with the contribution of the Provveditorato for the Public Works of Veneto, Trentino Alto Adige and Friuli Venezia Giulia, this study defined the Manila clam molecular mechanisms involved in the response to complex chemical mixtures characteristic of urban and industrial areas.

The management of dredged sediments in ports and lagoons must aim at avoiding potential impacts on marine ecosystems. Therefore, researchers must investigate the possible effects of complex mixtures of chemical contaminants present in sediments on animal species residing in lagoons and coastal areas.

Last author, Tomaso Patarnello explains, “Organisms exposed to polluted sediments, where PCBs concentrations were up to 120 times higher than in control areas, underwent significant alterations in the expression of genes involved in the response to complex chemical mixtures characteristic of urban and industrial areas. In particular, at the transcriptional level, we found a persistent activation of the mTORC1 signalling pathway, which is central in the coordination of cellular responses to chemical stress. We also observed the overrepresentation of potential pathogens and the upregulation of several pathways involved in the immune response of clams exposed to sediments from specific sites.

Corresponding author, Massimo Milan, concludes, “The results obtained highlight how the correct management of dredged sediments is essential for the conservation of this species and, more generally, how investigations conducted at a molecular level can also contribute to understanding the complexity of potential adverse effects on organisms inhabiting the Venice lagoon due to exposure to contaminated sediments.”

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

In the study, Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition researchers exposed clams to sediment samples collected from different sites within one of the Venice lagoon navigable canals close to the industrial area of Porto Marghera, as a means to define the molecular mechanisms behind sediment toxicity. Results reveal transcriptional and microbial changes of Manila clams after exposure to sediments. The work underlines how the correct management in the reuse of dredged sediments is crucial for the conservation of this species and possibly for other organisms inhabiting the Venice lagoon.

Thanks to the scientific activity performed in the Research Programme Venezia2021, coordinated by CORILA, with the contribution of the Provveditorato for the Public Works of Veneto, Trentino Alto Adige and Friuli Venezia Giulia, this study defined the Manila clam molecular mechanisms involved in the response to complex chemical mixtures characteristic of urban and industrial areas.

The management of dredged sediments in ports and lagoons must aim at avoiding potential impacts on marine ecosystems. Therefore, researchers must investigate the possible effects of complex mixtures of chemical contaminants present in sediments on animal species residing in lagoons and coastal areas.

Last author, Tomaso Patarnello explains, “Organisms exposed to polluted sediments, where PCBs concentrations were up to 120 times higher than in control areas, underwent significant alterations in the expression of genes involved in the response to complex chemical mixtures characteristic of urban and industrial areas. In particular, at the transcriptional level, we found a persistent activation of the mTORC1 signalling pathway, which is central in the coordination of cellular responses to chemical stress. We also observed the overrepresentation of potential pathogens and the upregulation of several pathways involved in the immune response of clams exposed to sediments from specific sites.

Corresponding author, Massimo Milan, concludes, “The results obtained highlight how the correct management of dredged sediments is essential for the conservation of this species and, more generally, how investigations conducted at a molecular level can also contribute to understanding the complexity of potential adverse effects on organisms inhabiting the Venice lagoon due to exposure to contaminated sediments.”

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

In the study, Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition researchers exposed clams to sediment samples collected from different sites within one of the Venice lagoon navigable canals close to the industrial area of Porto Marghera, as a means to define the molecular mechanisms behind sediment toxicity. Results reveal transcriptional and microbial changes of Manila clams after exposure to sediments. The work underlines how the correct management in the reuse of dredged sediments is crucial for the conservation of this species and possibly for other organisms inhabiting the Venice lagoon.

Thanks to the scientific activity performed in the Research Programme Venezia2021, coordinated by CORILA, with the contribution of the Provveditorato for the Public Works of Veneto, Trentino Alto Adige and Friuli Venezia Giulia, this study defined the Manila clam molecular mechanisms involved in the response to complex chemical mixtures characteristic of urban and industrial areas.

The management of dredged sediments in ports and lagoons must aim at avoiding potential impacts on marine ecosystems. Therefore, researchers must investigate the possible effects of complex mixtures of chemical contaminants present in sediments on animal species residing in lagoons and coastal areas.

Last author, Tomaso Patarnello explains, “Organisms exposed to polluted sediments, where PCBs concentrations were up to 120 times higher than in control areas, underwent significant alterations in the expression of genes involved in the response to complex chemical mixtures characteristic of urban and industrial areas. In particular, at the transcriptional level, we found a persistent activation of the mTORC1 signalling pathway, which is central in the coordination of cellular responses to chemical stress. We also observed the overrepresentation of potential pathogens and the upregulation of several pathways involved in the immune response of clams exposed to sediments from specific sites.

Corresponding author, Massimo Milan, concludes, “The results obtained highlight how the correct management of dredged sediments is essential for the conservation of this species and, more generally, how investigations conducted at a molecular level can also contribute to understanding the complexity of potential adverse effects on organisms inhabiting the Venice lagoon due to exposure to contaminated sediments.”

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

In the study, Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition researchers exposed clams to sediment samples collected from different sites within one of the Venice lagoon navigable canals close to the industrial area of Porto Marghera, as a means to define the molecular mechanisms behind sediment toxicity. Results reveal transcriptional and microbial changes of Manila clams after exposure to sediments. The work underlines how the correct management in the reuse of dredged sediments is crucial for the conservation of this species and possibly for other organisms inhabiting the Venice lagoon.

Thanks to the scientific activity performed in the Research Programme Venezia2021, coordinated by CORILA, with the contribution of the Provveditorato for the Public Works of Veneto, Trentino Alto Adige and Friuli Venezia Giulia, this study defined the Manila clam molecular mechanisms involved in the response to complex chemical mixtures characteristic of urban and industrial areas.

The management of dredged sediments in ports and lagoons must aim at avoiding potential impacts on marine ecosystems. Therefore, researchers must investigate the possible effects of complex mixtures of chemical contaminants present in sediments on animal species residing in lagoons and coastal areas.

Last author, Tomaso Patarnello explains, “Organisms exposed to polluted sediments, where PCBs concentrations were up to 120 times higher than in control areas, underwent significant alterations in the expression of genes involved in the response to complex chemical mixtures characteristic of urban and industrial areas. In particular, at the transcriptional level, we found a persistent activation of the mTORC1 signalling pathway, which is central in the coordination of cellular responses to chemical stress. We also observed the overrepresentation of potential pathogens and the upregulation of several pathways involved in the immune response of clams exposed to sediments from specific sites.

Corresponding author, Massimo Milan, concludes, “The results obtained highlight how the correct management of dredged sediments is essential for the conservation of this species and, more generally, how investigations conducted at a molecular level can also contribute to understanding the complexity of potential adverse effects on organisms inhabiting the Venice lagoon due to exposure to contaminated sediments.”

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

In the study, Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition researchers exposed clams to sediment samples collected from different sites within one of the Venice lagoon navigable canals close to the industrial area of Porto Marghera, as a means to define the molecular mechanisms behind sediment toxicity. Results reveal transcriptional and microbial changes of Manila clams after exposure to sediments. The work underlines how the correct management in the reuse of dredged sediments is crucial for the conservation of this species and possibly for other organisms inhabiting the Venice lagoon.

Thanks to the scientific activity performed in the Research Programme Venezia2021, coordinated by CORILA, with the contribution of the Provveditorato for the Public Works of Veneto, Trentino Alto Adige and Friuli Venezia Giulia, this study defined the Manila clam molecular mechanisms involved in the response to complex chemical mixtures characteristic of urban and industrial areas.

The management of dredged sediments in ports and lagoons must aim at avoiding potential impacts on marine ecosystems. Therefore, researchers must investigate the possible effects of complex mixtures of chemical contaminants present in sediments on animal species residing in lagoons and coastal areas.

Last author, Tomaso Patarnello explains, “Organisms exposed to polluted sediments, where PCBs concentrations were up to 120 times higher than in control areas, underwent significant alterations in the expression of genes involved in the response to complex chemical mixtures characteristic of urban and industrial areas. In particular, at the transcriptional level, we found a persistent activation of the mTORC1 signalling pathway, which is central in the coordination of cellular responses to chemical stress. We also observed the overrepresentation of potential pathogens and the upregulation of several pathways involved in the immune response of clams exposed to sediments from specific sites.

Corresponding author, Massimo Milan, concludes, “The results obtained highlight how the correct management of dredged sediments is essential for the conservation of this species and, more generally, how investigations conducted at a molecular level can also contribute to understanding the complexity of potential adverse effects on organisms inhabiting the Venice lagoon due to exposure to contaminated sediments.”

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

In the study, Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition researchers exposed clams to sediment samples collected from different sites within one of the Venice lagoon navigable canals close to the industrial area of Porto Marghera, as a means to define the molecular mechanisms behind sediment toxicity. Results reveal transcriptional and microbial changes of Manila clams after exposure to sediments. The work underlines how the correct management in the reuse of dredged sediments is crucial for the conservation of this species and possibly for other organisms inhabiting the Venice lagoon.

Thanks to the scientific activity performed in the Research Programme Venezia2021, coordinated by CORILA, with the contribution of the Provveditorato for the Public Works of Veneto, Trentino Alto Adige and Friuli Venezia Giulia, this study defined the Manila clam molecular mechanisms involved in the response to complex chemical mixtures characteristic of urban and industrial areas.

The management of dredged sediments in ports and lagoons must aim at avoiding potential impacts on marine ecosystems. Therefore, researchers must investigate the possible effects of complex mixtures of chemical contaminants present in sediments on animal species residing in lagoons and coastal areas.

Last author, Tomaso Patarnello explains, “Organisms exposed to polluted sediments, where PCBs concentrations were up to 120 times higher than in control areas, underwent significant alterations in the expression of genes involved in the response to complex chemical mixtures characteristic of urban and industrial areas. In particular, at the transcriptional level, we found a persistent activation of the mTORC1 signalling pathway, which is central in the coordination of cellular responses to chemical stress. We also observed the overrepresentation of potential pathogens and the upregulation of several pathways involved in the immune response of clams exposed to sediments from specific sites.

Corresponding author, Massimo Milan, concludes, “The results obtained highlight how the correct management of dredged sediments is essential for the conservation of this species and, more generally, how investigations conducted at a molecular level can also contribute to understanding the complexity of potential adverse effects on organisms inhabiting the Venice lagoon due to exposure to contaminated sediments.”

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The study published in the BMC Biology Journal by the Department of Comparative Biomedicine and Food Science of the University of Padua, in collaboration with Ca' Foscari University of Venice, investigates the potential risk and impact of sediment reuse on organisms inhabiting the Venice lagoon. The study focuses on the Manila clam (Ruditapes philippinarum), a filter-feeding mollusk species of high economic and ecological value for the Venice lagoon.

In the study, Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition researchers exposed clams to sediment samples collected from different sites within one of the Venice lagoon navigable canals close to the industrial area of Porto Marghera, as a means to define the molecular mechanisms behind sediment toxicity. Results reveal transcriptional and microbial changes of Manila clams after exposure to sediments. The work underlines how the correct management in the reuse of dredged sediments is crucial for the conservation of this species and possibly for other organisms inhabiting the Venice lagoon.

Thanks to the scientific activity performed in the Research Programme Venezia2021, coordinated by CORILA, with the contribution of the Provveditorato for the Public Works of Veneto, Trentino Alto Adige and Friuli Venezia Giulia, this study defined the Manila clam molecular mechanisms involved in the response to complex chemical mixtures characteristic of urban and industrial areas.

The management of dredged sediments in ports and lagoons must aim at avoiding potential impacts on marine ecosystems. Therefore, researchers must investigate the possible effects of complex mixtures of chemical contaminants present in sediments on animal species residing in lagoons and coastal areas.

Last author, Tomaso Patarnello explains, “Organisms exposed to polluted sediments, where PCBs concentrations were up to 120 times higher than in control areas, underwent significant alterations in the expression of genes involved in the response to complex chemical mixtures characteristic of urban and industrial areas. In particular, at the transcriptional level, we found a persistent activation of the mTORC1 signalling pathway, which is central in the coordination of cellular responses to chemical stress. We also observed the overrepresentation of potential pathogens and the upregulation of several pathways involved in the immune response of clams exposed to sediments from specific sites.

Corresponding author, Massimo Milan, concludes, “The results obtained highlight how the correct management of dredged sediments is essential for the conservation of this species and, more generally, how investigations conducted at a molecular level can also contribute to understanding the complexity of potential adverse effects on organisms inhabiting the Venice lagoon due to exposure to contaminated sediments.”

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2023RUB06 - Allegato 18 - Verbale 1 - Criteri

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2023PO185 Allegato 6 - Verbale 2 - Elenco candidati

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