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Dr Roberta Merlanti was born in Turin (Italy) on September, 25, 1974. She is an Italian citizen. She gradueted in Veterinary Medicine at the University of Padua (Italy) discussing the final thesis "Drug-metabolizing liver activity in veterinary species: species-specific differences". In 2001 she obtained the qualification in Veterinary Surgery. In 2002 she was winner of a three years PhD fellowship in Veterinary Public Health and Producing Animal Sciences at the University of Padua. In 2005 she obtained the PhD title in Veterinary Public Health and Producing Animal Sciences and she worked also as veterinary, collaborating on the management of some field projects, funded by the Regione del Veneto, as part of the "Research for the control and reppression of the illicit use of boldenone in beef cattle." From January 2005 to July 2008 she attended as a young researcher at the Department of Public Health, Comparative Pathology and Veterinary Hygiene, current Department of Comparative Biomedicine and Food Science, at the University of Padua, where she now attends as a senior researcher for the SS VET/07 (Veterinary Pharmacology and Toxicology). She teached in Vicenza “Xenobiotic residues in food and consumer safety".
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Orari di ricevimento
Il Lunedi' dalle 10:00 alle 11:00
presso Dipartimento di Biomedicina Comparata ed Alimentazione
Si prega di inviare una mail (roberta.merlanti@unipd.it) o telefonare (049-8272964) alcuni giorni prima preannunciandosi per evitare spiacevoli inconvenientiIl Venerdi' dalle 10:15 alle 11:00
presso Dipartimento di Biomedicina Comparata ed Alimentazione
Si prega di inviare una mail (roberta.merlanti@unipd.it) o telefonare (049-8272964) qualche giorno prima preannunciandosi onde evitare spiacevoli inconvenienti
Pubblicazioni
De Liguoro M, Di Leva V, Dalla Bona M, Merlanti R, Caporale G, Radaelli G (2012). Sublethal effects of trimethoprim on four freshwater organisms.. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, ISSN: 0147-6513, doi: 10.1016/j.ecoenv.2012.05.016
PEGOLO S, MERLANTI R., GIANTIN M, DACASTO M, MONTESISSA C, CAPOLONGO F (2010). High performance liquid chromatography determination of cytochrome P450 1A and 2C activities in bovine liver microsomes. THE VETERINARY JOURNAL, vol. 183, p. 81-88, ISSN: 1090-0233, doi: 10.1016/j.tvjl.2008.08.006
GALLINA G, POLTRONIERI C, MERLANTI R, DE LIGUORO M. (2008). Acute toxicity evaluation of four antibacterials with Daphnia magna. VETERINARY RESEARCH COMMUNICATIONS, vol. 32, p. S287-S290, ISSN: 0165-7380, doi: 10.1007/s11259-008-9130-2
MERLANTI R, GALLINA G, CAPOLONGO F, CONTIERO L, BIANCOTTO G, DACASTO M., MONTESISSA C (2007). An in vitro study on metabolism of 17 beta-boldenone and boldione using cattle liver and kidney subcellular fractions. ANALYTICA CHIMICA ACTA, vol. 586, p. 177-183, ISSN: 0003-2670, doi: 10.1016/j.aca.2006.12.007
GALLINA G, FERRETTI G, MERLANTI R, CIVITAREALE C, F. CAPOLONGO, DRAISCI R, MONTESISSA C (2007). Boldenone, boldione, and milk replacers in the diet of veal calves: The effects of phytosterol content on the urinary excretion of boldenone metabolites. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 55, p. 8275-8283, ISSN: 0021-8561, doi: 10.1021/jf071097c
DRAISCI R, MERLANTI R, FERRETTI G, FANTOZZI L, FERRANTI C, CAPOLONGO F, S. SEGATO, MONTESISSA C (2007). Excretion profile of boldenone in urine of veal calves fed two different milk replacers. ANALYTICA CHIMICA ACTA, vol. 586, p. 171-176, ISSN: 0003-2670, doi: 10.1016/j.aca.2007.01.026
CAPOLONGO F, TAPPARO M, MERLANTI R, RAVAROTTO L, TEALDO E, GALLINA G, MONTESISSA C, DACASTO M. (2007). Illicit treatments in cattle and urinary 6beta-hydroxycortisol/cortisol ratio. ANALYTICA CHIMICA ACTA, vol. 586, p. 228-232, ISSN: 0003-2670, doi: 10.1016/j.aca.2006.09.033
DRAISCI R, MONTESISSA C., SANTAMARIA B, DAMBROSIO C, FERRETTI G, MERLANTI R, FERRANTI C, DE LIGUORO M, CARTONI C, PISTARINO E, FERRARA L, TISO M, SCALONI A, COSULICH ME (2007). Integrated analytical approach in veal calves administered the anabolic androgenic steroids boldenone and boldione: urine and plasma kinetic profile and changes in plasma protein expression. PROTEOMICS, vol. 7, p. 3184-3193, ISSN: 1615-9853, doi: 10.1002/pmic.200601039
TOFFOLATTI L, ROSA GASTALDO L, PATARNELLO T, ROMUALDI C, MERLANTI R, MONTESISSA C., POPPI L, CASTAGNARO M, BARGELLONI L (2006). Expression analysis of androgen-responsive genes in the prostate of veal calves treated with anabolic hormones. DOME
Area di ricerca
Her research lines are:
-development of purification and extraction protocols of biological samples (plasma, urine, feces, liver, kidney, fat, muscle, honey, milk, ect) from different veterinary species (samples for HLPC and LC-MS analysis) to evaluate drug residues
-use of in vitro systems, such as hepatic and extraepatic subcellular fractions, to evaluate specie-specific metabolism of veterinary drugs and growth promoters
-development of HPLC analytical methods useful to determinate metabolic activity enzymes, such as Citochrome P450 (Ethoxyresorufin O-deethylation for CYP1A1; Testosterone hydroxylation for CYP3A and Tolbutamide methyl hydroxylation for CYP2C) in some producing animal species (bovine, rabbit, pig, fish, bivalves, ect)
-Identification in urine of markers of illicit treatments in beef cattle ( beta-boldenone alpha-/beta-testosterone, cortisol)
She is a Co-Author of 18 international publications with ISSN/ISBN, 19 posters at national and international conferences, 3 abstracts of communications at national and international conference.
Tesi proposte
- Messa a punto e validazione di un metodo in cromatografia liquida accoppiata alla spettrometria di massa per la quantificazione di isoflavoni e loro metaboliti in filetti di trota.
- Differenze specie-specifiche nel metabolismo in vitro di fluorochinoloni mediante analisi in cromatografia liquida accoppiata alla spettrometria di massa
