Giacomo Comiati read Italian philology and literature at the University of Padua, while also attending the Scuola Galileiana di Studi Superiori (the School of Excellence of Padua University). After obtaining his Ph.D. in Italian Studies at the University of Warwick (UK), he was a junior research fellow at the Dahlem Humanities Center of the Freie Universität in Berlin (Germany), and later a research fellow at the University of Oxford (UK), where he also was research associate to Corpus Christi College. He then worked as postdoctoral researcher at the University of Padua and La Sapienza University in Rome.

His research interests include Medieval and Early-Modern Italian literature (particularly poetry), Boccaccio and Petrarch Studies, Humanistic Latin and Italian textualities, Renaissance reception of Latin antiquity, Renaissance Latin poetry, and Early-Modern history of manuscript and print.

In 2025, he was awarded a MSCA Global Fellowship to carry out his LYRPO project (“Lyric Poetry in Venice in the Heterodox Renaissance, 1545-1657”) with Prof. Alessandro Metlica (Department of Literary and Linguistic Studies - University of Padua) and Prof. Eugenio Refini (NYU). LYRPO primarily aims to study the impact of Protestant ideas on lyric poetry produced in Catholic Venice in the Tridentine and Post-Tridentine era. It will investigate those Venetian lyric texts that dealt with religion, morality, and politics, while variously expressing heterodox thoughts, which tended not to be overtly heretical (to avoid censorship), yet were subtly influenced by Reformation-inspired ideas.