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MARIA CECILIA GIRON

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Position

Professoressa Associata

Structure

Dipartimento di Scienze del Farmaco - DSF

Address

VIA F. MARZOLO, 5 - PADOVA

Telephone

0498275091

E-mail

cecilia.giron@unipd.it

PRESENT POSITION
Assistant Professor of Pharmacology, Department of Pharmaceutical and Pharmacological Sciences (formerly Department of Pharmacology and Anesthesiology), School of Medicine, University of Padova
EDUCATION AND RESEARCH TRAINING
2003 Postdoctoral Fellow, Department of Pharmacology and Anesthesiology, University di Padova
2003 PhD Degree in Pharmacology and Toxicology, University of Padova
1998 Diploma of Specialization in Hospital Pharmacy (with full marks), University of Padova
1995-1996 Research Associate at the Department of Radiation Sciences, Mallinckrodt Institute of Radiology (MIR), Washington University School of Medicine, St. Louis, MO, USA
1995 Board Certified as Community Pharmacist
1995 MS Degree in Pharmaceutical Chemistry and Technology, University of Padova
1993-1994 EU COMETT Fellowship, PET Center, Groningen University Hospital, The Netherlands
1992 ERASMUS Fellowship at the Department of Organic and Molecular Inorganic Chemistry, University of Groningen, The Netherlands
LECTURER FOR THE FOLLOWING COURSES
Toxicology, BS Degree in Herbal Sciences, Faculty of Pharmacy (6 CFU, 2005-2013)
Basic Pharmacology, BS Degree in Radiological Technology, Faculty of Medicine (6 CFU, 2013)
Pharmacoepidemiology, MS Degree in Pharmacy, Faculty of Pharmacy (6 CFU, 2013)
General Pharmacology, MS Degree in Pharmaceutical Biotechnology, Faculty of Pharmacy (4 CFU, 2004-2007)
Radiopharmacy, Specialization Program in Hospital Pharmacy, Faculty of Pharmacy, University of Siena (2 CFU; 2012)
Radiopharmacology, Specialization Program in Nuclear Medicine, Faculty of Medicine (2 CFU; 2006-2013)
Advanced Pharmacology, Specialization Program in Anesthesiology and Intensive Care, Faculty of Medicine (1 CFU; 2006-2009)
EDUCATIONAL ACTIVITIES
Mentor in the PhD Program in Pharmacology and Therapy of the following Graduate Students: Anna Bin (2005-2008); Chiara Zoppellaro (2007-2009); Marsela Qesari (2010-2012); Valentina Caputi (2013-2015); Ilaria Marsilio (2015-2018), Silvia Cerantola (2017-2019).
2004-now Mentor of several MS Degree Thesis in Pharmacy and CTF and BS Degree in Herbal Sciences.
EDITORIAL RESPONSIBILITIES
Newsletter writer of SIF - Farmaci in evidenza, Italian Society of Pharmacology (SIF), http://edicola.sifweb.org/edicola/farmaci/pagina/archivio
Associate Editor for: Frontiers Molecular Biosciences, Section of Cellular Biochemistry, World Journal of Gastroenterology
Reviewer for: European Journal of Pharmacology, Frontiers in Pharmacology, Frontiers in Neuroscience, Neurogastroenterology and Motility, Journal of Nuclear Medicine, The Veterinary Journal, Acta Pharmacologica Sinica etc.
RESEARCH GRANTS
PI for: S. Camillo Hospital Treviso Research Grant (2014-2017), Alfawasserman Pharmaceutical Company (2014-2015), Cariparo Foundation (PhD Fellowship Grant, 2009-2011), University of Padova Research Grant (2004, 2008, 2009, 2017), European Union Center, University of Missouri – Columbia (USA, 2007) PRIN 2006, 2008, 2010.
OTHER APPOINTMENTS AND COMMITTEES
2014-present Consultant for the development of a “Guidance on Setting up Multimodality Preclinical Imaging Facilities: Associated Protocols and QA", International Atomic Energy Agency, United Nations (ONU), Vienna, Austria
2009-present National Coordinator of the Clinical Scientific Area Radiopharmacy for the Italian Society of Hospital Pharmacy (SIFO)
2008-2009 Regulatory Commission of Italian Ministry of Health as expert radiopharmacist


Notices

Office hours

  • Monday from 12:00 to 13:00
    at Dipartimento di Scienze del Farmaco, Edificio di Farmacologia, Largo Meneghetti n. 2 - 35131 Padova
    Si consiglia di prendere prima appuntamento via mail.

Teachings

Publications

EDITORIAL ACTIVITY
1. Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine, Editor U. Mazzi, Associate Editors M.C. Giron, A. Nadali, R.Rossin. Padova, SGE Editoriali, 2006, ISBN 88-89884-04-5.
2. Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine, Editor U. Mazzi, Associate Editors M.C. Giron, R.Rossin. Padova, SGE Editoriali, 2010.
3. Writer for “SIF-Farmaci in evidenza”, newsletter of the Italian Society of Pharmacology (http://www.sifweb.org/farmaci/sif_farmaci_evidenza_main.php).

PUBLICATIONS for years 2018-2016

1: Brun P, Qesari M, Marconi PC, Kotsafti A, Porzionato A, Macchi V, Schwendener
RA, Scarpa M, Giron MC, et al. Herpes Simplex Virus
Type 1 Infects Enteric Neurons and Triggers Gut Dysfunction via Macrophage
Recruitment. Front Cell Infect Microbiol. 2018 Mar 15;8:74.

2: Hung C, Bronec C, Napoli E, Graham J, Stanhope KL, Marsilio I, Giron MC, Havel
PJ, Giulivi C. Adipose depot-specific effects of ileal interposition surgery in
UCD-T2D rats: unexpected implications for obesity and diabetes. Biochem J. 2018
Feb 14;475(3):649-662.

3: Filpa V, Bistoletti M, Caon I, Moro E, Grimaldi A, Moretto P, Baj A, Giron MC,
et al. Changes in hyaluronan deposition in the rat myenteric plexus after experimentally-induced
colitis. Sci Rep. 2017 Dec 15;7(1):17644.

4: Antonioli L, Pellegrini C, Fornai M, Tirotta E, Gentile D, Benvenuti L, Giron
MC, et al. Colonic motor dysfunctions in a mouse model of high-fat diet-induced obesity: an involvement of A(2B) adenosine receptors. Purinergic Signal. 2017 Dec;13(4):497-510.

5: Caputi V, Marsilio I, Filpa V, Cerantola S, Orso G, Bistoletti M, et al. Antibiotic-induced
dysbiosis of the microbiota impairs gut neuromuscular function in juvenile mice.
Br J Pharmacol. 2017 Oct;174(20):3623-3639.

6: Brun P, Scarpa M, Marchiori C, Sarasin G, Caputi V, Porzionato A, Giron MC,
et al. Saccharomyces boulardii CNCM I-745 supplementation reduces gastrointestinal dysfunction in an animal model of IBS. PLoS One. 2017 Jul 21;12(7):e0181863.

7: Caputi V, Marsilio I, Cerantola S, Roozfarakh M, Lante I, et al. Toll-Like Receptor 4 Modulates Small Intestine Neuromuscular Function through Nitrergic and Purinergic Pathways. Front
Pharmacol. 2017 Jun 8;8:350.

8: Gabbia D, Dall'Acqua S, Di Gangi IM, Bogialli S, Caputi V, et al. The Phytocomplex from Fucus vesiculosus and Ascophyllum nodosum Controls Postprandial Plasma Glucose Levels: An In Vitro and In Vivo Study in a Mouse Model of NASH. Mar Drugs. 2017 Feb 15;15(2). pii: E41

9: Dall'Acqua S, Catanzaro D, Cocetta V, Igl N, Ragazzi E, Giron MC, Cecconello L, Montopoli M. Protective effects of ψ taraxasterol 3-O-myristate and arnidiol 3-O-myristate isolated from Calendula officinalis on epithelial intestinal barrier. Fitoterapia. 2016 Mar;109:230-5.


10: Antonioli L, Colucci R, Pellegrini C, Giustarini G, Sacco D, Tirotta E, Caputi V, Marsilio I, Giron MC, et al. The AMPK enzyme-complex: from the regulation of cellular energy homeostasis to a possible new molecular target in the management of chronic inflammatory disorders. Expert Opin Ther Targets. 2016;20(2):179-91.

Thesis proposals

1) Role of the enteric nervous system in animal models of neuropathy (Parkinson's disease, Crohn disease, ulcerative colitis, irritable bowel syndrome, psychiatric and neurological disorders)

2) Evaluation of drug or alimentary supplements in in vivo, ex vivo and in vitro gastrointestinal models

2) Pharmacoepidemiological studies for the prevention or management of clinical risk

3) Pharmacovigilance of durgs and medical devices