Address book
Contacts
LUCA FABRIS
Position
Professore Associato
Structure
Address
VIA GIUSTINIANI, 2 - PADOVA
Telephone

Notices
Office hours
Tuesday from 16:00 to 17:00
at Palasanità, room#27
Appuntamento da concordare via e-mail o al telefono (049-821-3131)
Teachings
- INTERNSHIP FOR MEDICAL LICENSE I - MEDICAL AREA, AA 2024 (MEP9086420)
- GENDER-SPECIFIC MEDICINE, AA 2024 (MEQ4106912)
- TEACHING ELECTIVE GENDER MEDICINE, AA 2023 (MEP8085240)
- GENDER-SPECIFIC AND EVIDENCE-BASED CLINICAL APPROACH, AA 2023 (MEQ3104202)
- TEACHING ELECTIVE GENDER MEDICINE, AA 2022 (MEP8085240)
- GENDER-SPECIFIC MEDICINE, AA 2022 (MEQ2100568)
- TEACHING ELECTIVE GENDER MEDICINE, AA 2021 (MEP8085240)
- TEACHING ELECTIVE GENDER MEDICINE, AA 2020 (MEP8085240)
- TEACHING ELECTIVE GENDER MEDICINE, AA 2019 (MEP8085240)
- TEACHING ELECTIVE GENDER MEDICINE, AA 2018 (MEP8085240)
- MEDICINE GENDER, AA 2017 (MEP4069018)
- PATHOLOGY OF THE DIGESTIVE SYSTEM IN THIS AREA, AA 2017 (MEP4068213)
- PATHOLOGY OF THE DIGESTIVE SYSTEM IN THIS AREA, AA 2017 (MEP4068213)
- PATHOLOGY OF THE DIGESTIVE SYSTEM IN THIS AREA, AA 2017 (MEP4068213)
- PATHOLOGY OF THE DIGESTIVE SYSTEM IN THIS AREA, AA 2017 (MEP4068213)
- PATHOLOGY OF THE DIGESTIVE SYSTEM IN THIS AREA, AA 2017 (MEP4068213)
- PATHOLOGY OF THE DIGESTIVE SYSTEM IN THIS AREA, AA 2016 (MEO2048724)
- PATHOLOGY OF THE DIGESTIVE SYSTEM IN THIS AREA, AA 2016 (MEO2048724)
- PATHOLOGY OF THE DIGESTIVE SYSTEM IN THIS AREA, AA 2016 (MEO2048724)
- PATHOLOGY OF THE DIGESTIVE SYSTEM IN THIS AREA, AA 2016 (MEO2048724)
- PATHOLOGY OF THE DIGESTIVE SYSTEM IN THIS AREA, AA 2016 (MEO2048724)
Research Area
The major goal of my research is to study the cell biology of biliary epithelial cells and apply this knowledge to understand the pathophysiology of biliary tree diseases (cholangiopathies). This goal is pursued within two specific areas of interest:
1. Genetic and immune-mediated cholangiopathies, as models of liver disease to study:
a) liver repair mechanisms, with focus on the role of ductular reaction as it relates to the progression of chronic biliary damage
b)epithelial-mesenchymal interactions and cross-talk mechanisms, with focus on the involvement of macrophages and fibrocytes in liver fibrosis
2. Cholangiocarcinoma, with main focus on mechanisms of cancer invasiveness, by unravelling:
a) tumor-stroma interactions and pro-invasive role of tumor reactive stroma
b) characterization of tumor biomarkers of enhanced invasive phenotype as tool for molecularly targeted therapies
c) development of animal models linking chronic inflammation to cancer
My scientific and professional interests extend to: 1) clinical management of rare liver diseases, 2) definition and application of outcome indicators (value-based medicine in hepatology) in immune-related liver diseases (AIH, PBC, PSC).
Thesis proposals
1) Gender-related differences in biliary repair: analysis of animal models and clinical correlates with human pathologies.
2) Unravelling the mechanisms of lymphatic dissemination in Cholangiocarcinoma: the role of tumor reactive stroma.
3) Phenotyping of Non Alcoholic Steatohepatitis (NASH)-associated Cholangiocarcinoma.