Address book

Contacts

Staff Structures

Position

Professoressa Associata

Address

VIA G. ORUS, 2 - PADOVA

Telephone

LAURA iop
Associate Professor

Master degree Medical Biotechnologies, 2005
Phd Clinical and Experimental, Medical Sciences, Curriculum of Cardiovascular Sciences, 2010

2005-2007 Graduate Fellowship in Heart Valve Regenerative Medicine, Dept. of Biomedical Sciences, University of Padua
2010-2012 Junior post-doc in Myocardial Regenerative Medicine, Dept. of Cardiac, Thoracic, and Vascular Sciences, University of Padua
2010-2012 Post-doc in Cardiac Disease Modeling, Dept. of Molecular Cardiology, Technical University of Munich
2013-2020 Scientific coordinator of the group of Cardiovascular Regenerative Medicine, Dept. of Cardiac, Thoracic, and Vascular Sciences, University of Padua
2013-2014 Senior Post-doc in Cardiovascular Regenerative Medicine, Dept. of Cardiac, Thoracic, and Vascular Sciences, University of Padua
2013-2016 Investigator of the FP7 European Project TECAS for the generation of tissue-engineered cardiovascular therapeutic solutions
2015-2016 Post-doc fellowship in Cardiovascular Regenerative Medicine, University Hospital of Padua and Venetian Institute of Molecular Medicine, Padua
2016-2019 Assistant Professor in Medical Technical Sciences, Dept. of Cardiac, Thoracic, and Vascular Sciences, University of Padua
2019- Assistant Professor in Applied Medical Technology and Methodology, Dept. of Cardiac Thoracic Vascular Sciences and Public Health, University of Padua
2020- Translation Biomedicine group, Dept. of Cardiac Thoracic Vascular Sciences and Public Health, University of Padua
2022- Associate Professor in Applied Medical Technology and Methodology, Dept. of Cardiac Thoracic Vascular Sciences and Public Health, University of Padua

Teaching activity:
- Co-tutor ‘Cardiovascular Regenerative Medicine’, Master Course in Medicine and Surgery and in Biotechnology, University of Padua, since 2005
- ‘Translational Regenerative Medicine’, Master Course in Medicine and Surgery, University of Padua, since 2016
- ‘Cardiac Tissue Engineering’, European Association Cardio-Thoracic Surgery Academy (2012-2017)
- ‘Biomedicine’ in 'Medical Semeiotic and Clinical Methodology', Master Course in Medicine and Surgery, University of Padua, since 2017
- 'Biology', in Chemistry, Biology, and Biochemistry, Master Course in Prevention Techniques in environment and work, University of Padua, since 2019
- 'Biology', in Physiology, Biochemistry, and Biology, Master Course in Nursing, University of Padua, since 2020
- 'Rehabilitation science', In Genetics and Microbiology, Master Course in Physiotherapy, University of Padua, since 2020

Teaching4Learning Academy:
- T4L (2019)
- T4L New Faculty (2019)
- Advanced T4L (2020)
- Change agent (2022)

Member of the Scientific Society ‘Society of Biomechanics’ since 2015
Member of the ESC Working Group on Cardiovascular Regenerative & Reparative Medicine, since 2020

Reviewer for Nature Regenerative Medicine, Acta Biomaterialia, Cytotechnology, Journal of Heart Valve Disease, Biomaterials, Journal of Cardiovascular Translational Research, Frontiers in Cardiovascular Medicine, Frontiers Cells and Developmental Biology

Expert reviewer for European Commission Projects

Editorial board member of Transplantology
Associate Editor Stem Cell Section of Frontiers Journals
Associate Editor Journal of Cardiovascular Translational Research
Associate Editor Prosthesis

Author of 54 peer-reviewed publications (51 indexed), and six book chapters. Current H-index: 23. Citation number: 1550

Notices

Office hours

  • Per fissare un appuntamento, contattare la docente via email (laura.iop@unipd.it).

Publications

Selected:

1: Iop L, et al. Xenotransplantation: The Way beyond and Ahead toward Clinical Application. J Immunol Res. 2018 Apr 4;2018:6191359.

2: Iop L, et al. The Rapidly Evolving Concept of Whole Heart Engineering. Stem Cells Int. 2017;2017:8920940.

3: Iop L, et al. The Light and Shadow of Senescence and Inflammation in Cardiovascular Pathology and Regenerative Medicine. Mediators Inflamm. 2017;2017:7953486.

4: Gallo M, et al. The Vietnamese pig as a translational animal model to evaluate tissue engineered heart valves: promising early experience. Int J Artif Organs. 2017 May 9;40(4):142-149.

5: Iop L, et al. Decellularized Cryopreserved Allografts as Off-the-Shelf Allogeneic Alternative for Heart Valve Replacement: In Vitro Assessment Before Clinical Translation. J Cardiovasc Transl Res. 2017 Apr;10(2):93-103.

6: Gallo M, al. Decellularized aortic conduits: could their cryopreservation affect post-implantation outcomes? A morpho-functional study on porcine homografts. Heart Vessels. 2016 Nov;31(11):1862-1873.

7: Iop L, et al. Guided tissue regeneration in heart valve replacement: from preclinical research to first-in-human trials. Biomed Res Int. 2015;2015:432901.

8: Iop L, et al. Decellularized allogeneic heart valves demonstrate self-regeneration potential after a long-term preclinical evaluation. PLoS One. 2014 Jun 18;9(6):e99593.

9: Jung CB, et al. Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia. EMBO Mol Med. 2012 Mar;4(3):180-91.

10: Iop L, et al. The influence of heart valve leaflet matrix characteristics on the interaction between human mesenchymal stem cells and decellularized scaffolds. Biomaterials. 2009 Sep;30(25):4104-16.

11: Rattazzi M, et al. Clones of interstitial cells from bovine aortic valve exhibit different calcifying potential when exposed to endotoxin and phosphate. Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2165-72.

12: Iop L, et al. Different cardiovascular potential of adult- and fetal-type mesenchymal stem cells in a rat model of heart cryoinjury. Cell Transplant. 2008;17(6):679-94.

Research Area

- Cardiovascular Regenerative Medicine
- Cardiovascular disease modeling
- Stem cells
- Biomaterials

Thesis proposals

Master thesis projects in Regenerative Medicine and Disease modeling of the cardiovascular system are available. Please contact Prof. Laura Iop (laura.iop@unipd.it) for more information.