Address book
Contacts
MARCO GIORGIO
Position
Professore Associato
Structure
Address
VIA U. BASSI, 58/B - PADOVA
Telephone
+39 049 827 6060
Marco Giorgio received the B.Sc. degree in Biology upon working on transgenic model of HBV at the University of Rome. He did the post-graduate training at the IRBM inPomezia, studying the biochemistry of IL-6. Awarded by a fellowship from AIRC, he investigated gene function and generated cancer models at the Regina Elena cancer institute. Then, for two years at the MSKCC in New York, he started working on the genetic link between cancer and aging. He received the PhD degree in Biotechnology discussing a thesis on the p66Shc aging gene and he joined the IEO in Milan, where, in the Department of Experimental Oncology, he continued investigating the mechanisms of aging involved in tumorigenesis and currently he collaborate to investigate the metabolism of metastasis.
Since 2018 he is associated professor of Biochemistry at the Department of Biomedical Science of the University of Padova where he studies the ageing bioenergetics and DNA metabolism.
Notices
https://www.biomed.unipd.it/en/ricerca/aree-tematiche/mitochondrial-pathophysiology/aging-signaling-pathways
https://www.facebook.com/agingresearchlab/
https://www.instagram.com/aging_research_lab/
https://www.research.ieo.it/research-and-technology/clinical-technoshots/clinical-technoshot-isolation-of-micrometastases-alive-cells/
https://www.research.ieo.it/research-and-technology/clinical-technoshots/clinical-technoshot-bioenergetics-analysis-platform/
Office hours
Friday from 10:00 to 12:00
at Laboratorio del docente, Via Ugo Bassi 58/B, polo "Vallisneri" - piano 6 ala est - stanza 63
Teachings
- NUTRITION AND METABOLIC PATHWAYS: FROM CELLS TO ORGANS, AA 2024 (AVQ1094683)
- NUTRITION AND METABOLIC PATHWAYS: FROM CELLS TO ORGANS, AA 2023 (AVQ1094683)
- BIOCHEMISTRY AND NUTRITION, AA 2022 (MEP9087178)
- NUTRITION AND METABOLIC PATHWAYS: FROM CELLS TO ORGANS, AA 2022 (AVQ1094683)
- NUTRITION AND METABOLIC PATHWAYS: FROM CELLS TO ORGANS, AA 2021 (AVQ1094683)
- BIOCHEMISTRY AND NUTRITION, AA 2020 (MEP9087178)
- BIOCHEMISTRY AND NUTRITION, AA 2019 (MEP9087178)
- BIOLOGY AND BIOCHEMESTRY, AA 2019 (MEN1033479)
- BIOLOGY AND BIOCHEMESTRY, AA 2018 (MEN1033479)
- HISTOLOGY AND BIOCHEMISTRY, AA 2018 (MEP3051647)
Publications
The studies of Prof. Marco Giorgio are reported in over 150 publications in international peer reviewed journals in the fields of biochemistry, molecular biology, physiology, genetics and medicine, cited 10000 times according to "Scopus - Orcid - Web of Science" (https://www.scopus.com/authid/detail.uri?authorId=6603620783).
Google Scholar link: https://scholar.google.com/citations?user=qDBFcb0AAAAJ&hl=en.
Among the 5 most relevant:
-Butelli et al. Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors. Nat Biotechnol. 2008.26:1301-8.
-Pinton et al. Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc. Science. 200. 315:659-63.
-Giorgio et al. Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell.2005.122:221-33.
-Migliaccio et al. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature.1999.402:309-13.
-Wang et al. Role of PML in cell growth and the retinoic acid pathway. Science.1998.279:1547-51.
Research Area
Molecular mechanisms of aging, focusing particularly on the physiopathological mechanisms of adaptation to the environment that reshape the energetic and DNA metabolism and the redox balance.
https://www.biomed.unipd.it/ricerca/aree-tematiche/mitochondrial-pathophysiology/aging-signaling-patways
Thesis proposals
Role and molecular mechanisms of physical exercise in colorectal cancer prevention.
Pathogenic mechanisms of steroid hormones in sport.
Branched chain amino acids integration as a means to obtaining a muscle mass increase: risks and benefits.
Role of microbiota in the development of the osteo-articular fragility in the elderly and the effects of physical exercise.
The underestimated relevance of the intake and the origin of carbohydrates in a middle-distance athlete’s performance.
Bacteria in movements: the lowest quantity of physical activity required in order to improve the composition and functionality of the gut microbiota in obese and overweight people, avoiding the worsening of their low grade chronic inflammation.
Role of gut microbiota exercise-induced changes in cardiovascular risk prevention.
The characteristics of the optimum physical activity program for patients with type 1 diabetes.