NAME: Susanna MANDRUZZATO PRESENT APPOINTMENT: Associate Professor of Immunology, Department of Surgery, Oncology and Gastroenterology, Oncology and Immunology Section, University of Padova, Italy.QUALIFICATIONS: -Pharmaceutical Chemistry degree, 1989-PhD in Oncology, University of Padova, 1999PREVIOUS APPOINTMENTS : -Institute of General Pathology, University of Padova, Italy, 1989 - 1990-Institute of Oncology, Chair of Immunology, University of Padova, Italy, 1990- 1994-Investigator, Ludwig Institute for Cancer Research (Brussels Branch) - Brussels, Belgium 1994 -1997 -Assistant Professor of Immunology, Department of Surgery, Oncology and Gastroenterology, University of Padova, 2006-2018POSTGRADUATE AWARDS AND FELLOWSHIPS: - Fellowship "Italian consortium for antitumoral vectors" 1990 - 1992- Fellowship "Italian association for cancer research" 1993 -1994- Post doctoral fellowship : Training and Mobility of Researchers (TMR), 1996.- Post-doctoral fellowship : ICGEB 1998-1999- Post-doctoral fellowship, University of Padova. 2000-2001- UICC post-doctoral fellowship, October 2003- Collaborative research contract with Padova University, 2001-2003 LEARNED SOCIETIES: - CIP, CIMT Immunoguiding Program. Member of the steering Committee.-SIICA, Italian Society of Immunology, Clinical Immunology and Allergology- IMI, Italian Melanoma IntergroupMAJOR RESEARCH INTERESTS :-Role of adaptive immune response in different mouse models and implications for adoptive cell therapy. (Rosato et al., Int J Cancer, 1992; Zanovello et al., Cancer Immunol Immunother., 1992; Mandruzzato et al., Pharmacological Res., 1192; Pollis et al. Pharmacological Res., 1992; Rosato et al., Leukemia/s, 1992; Pollis et al. Leukemia/s, 1992; Mandruzzato et al., Cancer Res., 1994; Rosato et al., Int J Cancer, 1995; Rosato et al., Int J Cancer, 1996) -Tumor antigens recognized by cytotoxic T lymphocytes: molecular identification and characterization of their role in cancer patients. (Herman et al., Immunogenetics, 1996; Mandruzzato et al., J. Exp. Med.,1997; Dalerba et al., Int J Cancer, 2001; Zambon et al., Cancer, 2001; Mandruzzato et al., J Immunol, 2002, Rosato et al., Int J Cancer). -Analysis of genes and miRNA expression in tumors and their role in tumor progression. (Wang et al., J Transl Med., 2004; Basil et al., Cancer Res., 2006; Mandruzzato et al., J Transl Med., 2006; Indraccolo et al., J Immunol., 2007; Mandruzzato Adv Exp Med Biol., 2007; Crende et al., Am J Pathol., 2013; Pizzini et al., BMC Genomics, 2013; Bisognin et al., Mol Onc., 2014; Perilli et al., Oncotarget, 2014; Perilli et al., Genomics Data, 2014).-Immune-evasion in cancer: role of myeloid-derived suppressor cells (MDSC). (Bronte et al., Immunol Invest, 2006; Mandruzzato et al., J. Immunol., 2009; Peranzoni et al., Curr Opin Immunol 2010; Marigo et al., Immunity, 2010; Chioda et al., Cancer Metastasis Rev, 2011; Solito et al., J Leukoc Biol., 2011; Solito et al., Blood, 2011; Montero et al., J Immunother., 2012; Walter et al., Nature Medicine, 2012; Solito et al., Immunol Invest, 2012; Ugel et al., Cell Reports, 2012; Zoso et al., Eur. J. Immunol., 2014; Mazza et al. Genomics Data, 2014; Solito et al., Annals of the NY Academy of Sc, 2014; Damuzzo et al., Cytometry part B, 2015; Ugel et al., J. Clin. Invest., 2015; Pinton et al., Oncotarget, 2015; Mandruzzato et al., Cancer Immunol. Immunother., 2016; Solito et al., J. of Pathol., 2017, Pinton et al., OncoImmunology, 2018

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