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ENRICO GRINGERI

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Position

Professore Associato

Structure

Dipartimento di Scienze Chirurgiche Oncologiche e Gastroenterologiche - DiSCOG

Address

VIA GIUSTINIANI, 2 - PADOVA

Telephone

0498218547

E-mail

enrico.gringeri@unipd.it

ENRICO GRINGERI, MD PhD
Date and place of birth: 12/03/1971, Messina Italy (CF: GRNNRC71C12F158D)
Profession: Medical Doctor, Specialist in General Surgery, Associate Professor of Surgery, University of Padova
Affiliation: Department of Surgical Oncological and Gastroenterological Sciences - Hepatobiliary Surgery and Liver Transplant Unit,
CARREER
• 1998,MedicalDegree
• 2004SpecialistinGeneralSurgery
• 2008PhDMedicalandExperimentalSciences,SurgicalandTechnologicalApplication (XX
course)
• from2004,ClinicalCoordinatorHepatobiliaryandLiverTransplantUnit(ChiefProf.U.Cillo),
Department of General Surgery and Organ Transplantation (University of Padova)
• June2006-2012,MemberScientificCommitteeoftheInter-DepartmentalCenterof
Experimental Surgery at the University of Padova
• March2009,AssistantProfessorofSurgery,UniversityofPadova
• from2012MemberoftheScientificBoardatthe“AssociazioneSofia”
• 2013,AggregateProfessorofSurgery,UniversityofPadova
• from2013,Secretaryatthe“30NodiperilFegato”Association
• from2014MemberoftheAcademicboardofPhDattheClinicalandExperimentalSciences
course, Department of Medicine, University of Padova
• October2015,AssociateProfessorofSurgery,UniversityofPadova
• FromFebruary2015AdviserofSIRC(SocietàItalianaRicercheinChirurgia)
• From2015ElectedMemberoftheBoardattheDepartmentofSurgicalOncologicaland
Gastroenterological Sciences (DiSCOG), University of Padova
VISITING CLINICAL OBSERVER
• HepatobiliopancreaticServiceofMemorialSloanKetteringCancerCenter,NewYork,NY-USA
(Chief Dr. W.R. Jarnagin), Novembre 2009
• HepatobiliopancreaticSurgeryandLiverTransplantUnit.MountSinaiHospital,NewYork,NY-
USA (Chief Dr. M. Schwartz), Novembre 2009
• HepatobiliopancreaticServiceofMemorialSloanKetteringCancerCenter,NewYork,NY-USA
(Chief Dr. W.R. Jarnagin), Marzo 2011
• MayoClinicTransplantCenter,Rochester,MN-USA(ChiefDr.C.Rosen),Marzo2011
ACADEMIC AND RESEARCH ACTIVITY
• fromJanuary2006,Responsibleofteachingin“SurgicalPhysiopathologyandExperimental
Surgery” (2° year) and “Surgical Techniques part II” (3° year) at the Residency School of General Surgery (1^ – Director Prof. D.F. D’Amico) at the Department of General Surgery and Organ Transplantation, 1^ Surgical Clinic, University of Padova
• Responsibleofteachingin“GeneralSurgery”attheNurseSchool,UniversityofPadova Thesis supervisor at the University of Padova, Medical School
• Sub-investigatoranddatamanagerwithexperiencesonclinicaltrialsconcerninglivertransplant conducted according to ICH/GCP
• Basicandpreclinicalscience,fieldsofinterest:ischemic-reperfusioninjury,hepaticregeneration and prevention of fibrosis, extreme hepatic resection in small and large animal models, biomarkers and oncogenesis
• EducationonGoodScientificPractice(GSP)accordingtotheprinciplesofintegrityandhonesty (last investigator meeting participation in April 2014)
• AuthorandcoAuthor:1monographyand3studenttext-books
• AuthorandcoAuthor:morethan200nationalandinternationalscientificpublications(72peer-
reviewed papers)
• IF:194,28
• H-index:17
• Memberofnationalandinternationalscientificsocieties(AIS,SIC,SIRC,SITO,HPB,ILTS)
GRANTS AWARDED
• 2013 - Study of molecular markers that are critical m

Notices

POSSIBILITY TO ATTEND HEPATOBILIOPANCRETIC SURGERY AND LIVER TRANSPLANT OR CLINICAL ACTIVITIES. PARTICIPATION IN MULTIDISCIPLINARY MEETING

Office hours

  • Monday from 17:00 to 18:00
    at Presso il proprio studio sito al 7° piano del Policlinico
    ricevimento previo appuntamento concordato via mail: enrico.gringeri@unipd.it

  • Friday from 16:00 to 17:00
    at Presso il proprio studio sito al 7° piano del Policlinico
    ricevimento previo appuntamento concordato via mail: enrico.gringeri@unipd.it

Teachings

Publications

1: Cillo U, Gringeri E, Feltracco P, Bassi D, D'Amico FE, Polacco M, Boetto R.
Totally Laparoscopic Microwave Ablation and Portal Vein Ligation for Staged
Hepatectomy : A New Minimally Invasive Two-Stage Hepatectomy. Ann Surg Oncol.
2015 Aug;22(8):2787-8. doi: 10.1245/s10434-014-4353-7. Epub 2015 Jan 21. PubMed
2: Gringeri E, Boetto R, DʼAmico FE, Bassi D, Cillo U. Laparoscopic microwave
ablation and portal vein ligation for staged hepatectomy (LAPS): a minimally
invasive first-step approach. Ann Surg. 2015 Feb;261(2):e42-3. doi:
10.1097/SLA.0000000000000606. PubMed PMID: 24651131.
3: Gringeri E, Boetto R, Bassi D, D'Amico FE, Polacco M, Romano M, Neri D,
Feltracco P, Zanus G, Cillo U. Laparoscopic microwave thermal ablation for late
recurrence of local hepatocellular carcinoma after liver transplant: case report.
Prog Transplant. 2014 Jun;24(2):142-5. doi: 10.7182/pit2014632. PubMed PMID:
4: Gringeri E, Boetto R, Bassi D, D'Amico FE, Polacco M, Romano M, Barbieri S,
Feltracco P, Spampinato M, Zanus G, Cillo U. Totally laparoscopic caudate lobe
resection: technical aspects and literature review. Surg Laparosc Endosc Percutan
Tech. 2014 Dec;24(6):e233-6. doi: 10.1097/01.sle.0000442525.26905.6d. Review.
5: Gringeri E, D'Amico FE, Bassi D, Mescoli C, Bonsignore P, Boetto R, Lodo E,
Noaro G, Polacco M, D'Amico F, Boccagni P, Zanus G, Brolese A, Cillo U. Liver
transplantation for massive hepatomegaly due to polycystic liver disease: an
extreme case. Transplant Proc. 2012 Sep;44(7):2038-40. doi:
10.1016/j.transproceed.2012.06.041. PubMed PMID: 22974902.
6: Gringeri E, Bonsignore P, Bassi D, D'Amico FE, Mescoli C, Polacco M, Buggio M,
Luisetto R, Boetto R, Noaro G, Ferrigno A, Boncompagni E, Freitas I, Vairetti MP,
Carraro A, Neri D, Cillo U. Subnormothermic machine perfusion for
non-heart-beating donor liver grafts preservation in a Swine model: a new
strategy to increase the donor pool? Transplant Proc. 2012 Sep;44(7):2026-8. doi:
10.1016/j.transproceed.2012.06.014. PubMed PMID: 22974898.
7: Gringeri E, Polacco M, D'Amico FE, Bassi D, Boetto R, Tuci F, Bonsignore P,
Noaro G, D'Amico F, Vitale A, Feltracco P, Barbieri S, Neri D, Zanus G, Cillo U.
Liver autotransplantation for the treatment of unresectable hepatic metastasis:
an uncommon indication-a case report. Transplant Proc. 2012 Sep;44(7):1930-3.
doi: 10.1016/j.transproceed.2012.06.032. PubMed PMID: 22974875.
8: Gringeri E, Bassi D, D'Amico FE, Boetto R, Polacco M, Lodo E, D'Amico F,
Vitale A, Boccagni P, Zanus G, Cillo U. Neoadjuvant therapy protocol and liver
transplantation in combination with pancreatoduodenectomy for the treatment of
hilar cholangiocarcinoma occurring in a case of primary sclerosing cholangitis:
case report with a more than 8-year disease-free survival. Transplant Proc. 2011
May;43(4):1187-9. doi: 10.1016/j.transproceed.2011.01.140. PubMed PMID: 21620084.
9: Gringeri E, Polacco M, D'Amico FE, Scopelliti M, Bassi D, Bonsignore P,
Luisetto R, Lodo E, Carraro A, Zanus G, Cillo U. A new liver autotransplantation
technique using subnormothermic machine perfusion for organ preservation in a
porcine model. Transplant Proc. 2011 May;43(4):997-1000. doi:
10.1016/j.transproceed.2011.01.139. PubMed PMID: 21620035.
10: Gringeri E, Carraro A, Tibaldi E, D'Amico FE, Mancon M, Toninello A, Pagano
MA, Vio C, Cillo U, Brunati AM. Lyn-mediated mitochondrial tyrosine
phosphorylation is required to preserve mitocho

Research Area

1) ONCOLOGICAL SURGERY: HEPATOCARCINOMA, COLANGIOCARCINOMA,LIVER METASTASIS

2) TISSUE ENGINEERING, STEM CELLS AND ORGAN PRESERVATION

3) TRANSPLANT IMMUNOLOGY

4) EXTREME LIVER SURGERY: EX-VIVO EX-SITU LIVER RESECTIONS (AUTO-TRANSPLANTATION), TOTAL VASCULAR EXCLUSION LIVER RESECTION, VASCULAR RECONSTRUCTIONS, TWO-STAGE LIVER RESECTION

5) LIVER REGENERATION AND FIBROSIS

6) EXPERIMENTAL SURGERY: REALIZATION OF LIVER TRANSPLANT AND LIVER AUTOTRANSPLANTATION MODELS. EXTREME LIVER RESECTION IN SMALL AND LARGE ANIMAL






Thesis proposals

1. LAPAROSCOPIC LIVER RESECTION: A RETROSPECTIVE ANALYSIS OF A PROSPECTICALLY COMPILED DATABASE

2.LAPAROSCOPIC LIVER RESEATION VS OPEN LIVER RESECTION FOR HEPATOCARCINOMA AS A BRIDGE TO THE LIVER TRANSPLANTATION

3.LIVER RETRANSPLANTATION: CENTER EXPERIENCE AND RISK FACTORS ANALYSIS

4. IDENTIFICATION OF BIOMARKERS INVOLVED IN THE PROCESS OF OVERFLOW VASCULAR DAMAGE AFTER EXTREME LIVER RESECTION IN SMALL ANIMAL MODELS

5. MACHINE PERFUSION IN LIVER TRANSPLANTATION

6. MACHINE PERFUSION IN EX-SITU LIVER RESECTION

7. IDENTIFICATION OF NEW BIOMARKERS WITH PROGNOSTIC MEANING IN THE PERIHILAR CHOLANGIOCARCINOMA