Address book
Contacts
MERY GIANTIN
Position
Professoressa Associata
Address
VIALE DELL'UNIVERSITA', 16 - LEGNARO PD
Telephone
0498272946
Born in Dolo (Venice, Italy) on February 22nd, 1980.
Sep 2004: Degree in Veterinary Medicine (DVM) at the Faculty of Veterinary Medicine of Padua (Italy), marks 110/110 cum laude
Oct 2004: stage in the "Laboratoire de Pharmacologie et Toxicologie (Pharmacologie Moléculaire), Institut National de la Recherche Agronomique (INRA, UR66)" in Toulouse (France)
Oct 2006 – Dec 2011: Assistant Professor in Veterinary Pharmacology and Toxicology, UNIPD (Italy), Department of Public Health, Comparative Pathology and Food Hygiene
Oct 2006 - Mar 2007: Visiting Researcher (6 months) at the "Laboratoire de Pharmacologie et Toxicologie (Pharmacologie Moléculaire), Institut National de la Recherche Agronomique (INRA)" in Toulouse (France)
Mar 2008: Doctor of Philosophy (PhD) in Veterinary Sciences (Public Health and Comparative Pathology), UNIPD (Italy)
Jan 2012 – Jan 2015: Assistant Professor in Veterinary Pharmacology and Toxicology, Department of Comparative Biomedicine and Food Science (Dept. BCA), UNIPD
Feb 2014: National Scientific Qualification as Associate Professor in the sector 07/H4 – Clinical Veterinary Medicine and Pharmacology
Feb 2015 - present: Associate Professor in Veterinary Pharmacology and Toxicology, Dept. BCA, UNIPD
Jun 2021: National Scientific Qualification as Full Professor in the sector 07/H4 – Clinical Veterinary Medicine and Pharmacology
RESEARCH INTERESTS:
- comparative in vitro and in vivo studies on the expression and regulation of drug metabolizing enzymes and drug transporters;
- molecular and cellular toxicity of xenobiotics (natural toxins, emerging contaminants);
- toxicogenomics;
- veterinary and comparative oncology and target therapy;
- nutrigenomics.
For some research topics grants from the Department, UNIPD and public authorities have been obtained
Author or co-author of 81 indexed articles.
TEACHING EXPERIENCES:
- Module “Toxicology” of the course “Food, food-correlated pathologies and Toxicology”, Bachelor Degree in Biotechnologies (UNIPD);
- Module “Pharmacogenetics, Toxicogenomics and In Vitro Toxicology” of the course “Food Toxicology and Food Regulation”, Master of Science in Biotechnologies for Food Science (UNIPD);
- Module of the course "Laboratory animal care in clinical settings and pain assessment", Bachelor Degree in Animal Care (UNIPD).
- Supervisor of undergraduated students (Bachelor Degree in Biotechnologies, Master of Science in Biotechnologies for Food Science and Veterinary Medicine)
- Coordinator of the Scientific Research Committee of BCA Dept. (2019-);
- Member of the Board of the PhD School in Veterinary Sciences and Food Safety, UNIPD (2015-);
- Member of the Joint Committee of the School in Agricultural Sciences and Veterinary Medicine, UNIPD (2016-2019);
- Member of Internship and Degree Committee, Master of Science in Biotechnologies for Food Science, UNIPD (2009-2023);
- Member of the Education Resources Committee, Dept. BCA, UNIPD (2015-2023).
Notices
Office hours
at studio del docente
previo appuntamento
Teachings
- FOOD TOXICOLOGY AND TOXICOGENOMICS, AA 2024 (AVQ2100543)
- FOOD TOXICOLOGY AND TOXICOGENOMICS, AA 2023 (AVQ2100543)
- TOXICOGENOMICS AND TOXICOLOGIC PATHOLOGY, AA 2020 (AVP6075240)
- TOXICOGENOMICS AND TOXICOLOGIC PATHOLOGY, AA 2019 (AVP6075240)
- FOOD TOXICOLOGY AND FOOD REGULATION, AA 2017 (AVP5073779)
- TOXICOGENOMICS AND TOXICOLOGIC PATHOLOGY, AA 2017 (AVP6075240)
- XENOBIOTIC RESIDUES AND TOXICOLOGIC PATHOLOGY, AA 2016 (MVO2045631)
- XENOBIOTIC RESIDUES AND TOXICOLOGIC PATHOLOGY, AA 2015 (MVO2045631)
Publications
Most relevant publications concerning different research interests:
Pauletto M, Giantin M, Tolosi R, ... Zaghini A, Dacasto M. Discovering the Protective Effects of Quercetin on Aflatoxin B1-Induced Toxicity in Bovine Foetal Hepatocyte-Derived Cells (BFH12). Toxins, 2023, 15:555. doi: 10.3390/toxins15090555.
Iori S, Pauletto M, Bassan I, ... Dacasto M, Giantin M. Deepening the Whole Transcriptomics of Bovine Liver Cells Exposed to AFB1: A Spotlight on Toll-like Receptor 2. Toxins, 2022, 14:504. doi: 10.3390/toxins14070504.
Zorzan E, Elgendy R, Guerra G, ... Dacasto M, Giantin M. Hypermethylation-Mediated Silencing of CIDEA, MAL and PCDH17 Tumour Suppressor Genes in Canine DLBCL: From Multi-Omics Analyses to Mechanistic Studies. International Journal of Molecular Science, 2022, 23:4021. doi: 10.3390/ijms23074021.
Ceschi S, Berselli M, Cozzaglio M , ... Spolaore B, Sissi C. Vimentin binds to G-quadruplex repeats found at telomeres and gene promoters. Nucleic Acids Research, 2022, 50:1370–1381. doi: 10.1093/nar/gkab1274.
Pascual A, Pauletto M, Trocino A, ... Pillan G, Xiccato G. Effect of the dietary supplementation with extracts of chestnut wood and grape pomace on performance and jejunum response in female and male broiler chickens at different ages. Journal of Animal Science and Biotechnology, 2022, 13:102. doi: 10.1186/s40104-022-00736-w.
Da Ros S, Nicoletto G, Rigo R, ... Giantin M, Sissi C. G-quadruplex modulation of SP1 functional binding sites at the KIT proximal promoter. International Journal of Molecular Sciences, 2021, 22:1–14. doi: 10.3390/ijms22010329.
Pascual A, Pauletto M, Giantin M, ... Xiccato G, Trocino A. Effect of dietary supplementation with yeast cell wall extracts on performance and gut response in broiler chickens. Journal of Animal Science and Biotechnoly, 2020, 11:40. doi: 10.1186/s40104-020-00448-z.
Giantin M, Rahnasto-Rilla M, Tolosi R, ... Honkakoski P, Dacasto M. Functional impact of cytochrome P450 3A (CYP3A) missense variants in cattle. Scientific Reports, 2019, 9:19672. doi: 10.1038/s41598-019-56271-8.
Giantin M, Küblbeck J, Zancanella V, ... Dacasto M, Honkakoski P. DNA elements for constitutive androstane receptor- and pregnane X receptor-mediated regulation of bovine CYP3A28 gene. PLoS One, 2019, 14:e0214338. doi: 10.1371/journal.pone.0214338.
Pauletto M, Lopparelli RM, Pegolo S, ... Mutinelli F, Dacasto M. Significance of the goby Zosterisessor ophiocephalus as a sentinel species for Venice Lagoon contamination: Combining biomarker responses and bioaccumulation. Science of Total Environment, 2019, 660:959-973. doi: 10.1016/j.scitotenv.2019.01.033.
Giannuzzi D, Marconato L, Elgendy R, ... Dacasto M, Aresu L. Longitudinal transcriptomic and genetic landscape of radiotherapy response in canine melanoma. Vet Comp Oncol. 2019 Sep;17(3):308-316. doi: 10.1111/vco.12473.
Da Ros S, Aresu L, Ferraresso S, ... Dacasto M, Giantin M. Validation of epigenetic mechanisms regulating gene expression in canine B-cell lymphoma: An in vitro and in vivo approach. PLoS One, 2018, 13:e0208709. doi: 10.1371/journal.pone.0208709.
Zorzan E, Elgendy R, Giantin M, Dacasto M, Sissi C. Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule. Scientific Reports, 2018, 8:17107. doi: 10.1038/s41598-018-35516-y.
Research Area
Research interests
a. Comparative in vitro and in vivo studies on the expression and regulation of drug metabolizing enzymes (cytochrome P450, conjugative enzymes, drug transporters).
b. Molecular toxicology of xenobiotics.
c. Toxicogenomics and pharmacogenetics.
d. Comparative oncology and target therapy.
e. Nutrigenomics.
