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Rubrica

Personale Strutture

Qualifica

Ricercatore a tempo det. art. 24 c. 3 lett. B L. 240/2010

Indirizzo

VIA G. ORUS, 2 - PADOVA

Telefono

FORMAZIONE
2009 Ph.D. in Molecular Medicine: Università di Trieste, Trieste, Italia
2004 Laurea (ciclo unico) in Biotecnologie Mediche: Università di Trieste

ESPERIENZE LAVORATIVE
2022-present Ricercatore a td di tipo B (RTDb), Dipartimento di Biologia, Università di Padova
2020-2022 MSCA Fellow, Dipartimento di Biologia, Università di Padova
2019-present Principal Investigator, Istituto Veneto di Medicina Molecolare (VIMM), Padova
2018-2019 Research Associate, Cancer Biology Department, University of Pennsylvania
2013-2017 Postdoctoral Fellow, Cancer Biology Department, UPenn. Mentor: K.E. Wellen
2009-2012 Postdoctoral Fellow, Molecular Medicine Laboratory at ICGEB, Trieste. Mentor: M. Giacca
2005-2009 Ph.D. student, Molecular Medicine laboratory at ICGEB, Trieste, Italy. Mentor: M. Giacca

AWARDS
2020 Marie Sklodowska-Curie Action (MSCA) Fellowship: Project OPEN P-CAN
2019 Seal of Excellence – MSCA Fellowships Program
2018 INROAd mobility award – University of Pavia
2018 AIRC iCARE-2 Fellowship (EU Cofund program)
2017 Travel Award – International Society Cancer Metabolism
2011 Scholar-In-Training Award at AACR Conference on Tumor Microenvironment Complexity, Orlando.
2010 Scholar-In-Training Award at MRS-AACR Conference on Metastasis and Tumor Microenvironment, Philadelphia.
2008 “AtaxiaUK” long-term fellowship.

MEMBERSHIP OF SCIENTIFIC SOCIETIES
2017 – present Membro e Board of Directors, International Society of Cancer Metabolism (ISCaM)
2019 – present Membro, Società Italiana di Biofisica e Biochimica Molecolare (SIBBM)
2020 - present Membro, Società Italiana di Cancerologia (SIC)
2020 - present Membro, European Association of Cancer Research (EACR)
2021 - present Membro fondatore, Italian Pancreatic Cancer Community (I-PCC)

FUNDING
2019-2020 iCARE AIRC
2020-2022 R21 NCI-NIH
2020-2024 MFAG-AIRC
2020-2023 WorldWide Cancer Research
2021-2022 TNA-EASI genomics
2022-2023 WCRF

Avvisi

Orari di ricevimento

  • Il Giovedi' dalle 14:00 alle 17:00
    presso Istituto Veneto di Medicina Molecolare (VIMM), via Orus 2, Padova

Pubblicazioni

Carrer A, Lee JV, Shah S, Snyder NW, Wei S, Venneti S, Worth AJ, Yuan ZF, Lim HW, Liu S, Jackson E, Aiello NM, Haas NB, Rebbeck TR, Judkins A, Won KJ, Chodosh LA, Garcia BA, Stanger BZ, Feldman MD, Blair IA, Wellen KE, Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation, Cell Metabolism, 2014

Carrer A, Wellen KE, Metabolism and epigenetics: a link cancer cells exploit, Curr Opin Biotechnol. 2014

Zhao S, Torres T, Henry R, Trefely S, Wallace M, Lee JV, Carrer A, Sengupta A, Campbell SL, Kuo Y-M, Frey AJ, Meurs N, Viola JM, Blair IA, Weljie AM, Metallo CM, Snyder NW, Andrews AJ, Wellen KE, ATP-citrate lyase controls a glucose-to-acetate metabolic switch, Cell Reports, 2016

Carrer A, Parris JLD, Trefely S, Henry RA, Montgomery D, Kuo Y-M, Blair IA, Meier JL, Andrews Aj, Snyder NW, and Wellen KE, Impact of high fat diet on tissue acyl-CoA and histone acetylation levels, Journal of Biological Chemistry, 2017

McDonald O, Saunders T, Tryggvadottir R, Mentch S, Warmoes M, Word A, Carrer A, Salz T, Natsume S, Stauffer K, Makohon-Moore A, Zhong Y, Wu H, Wellen KE, Locasale JD, Iacobuzio-Donahue C, Li X, Large-scale epigenomic reprogramming links anabolic glucose metabolism to distant metastasis during the evolution of pancreatic cancer progression, Nature Genetics, 2017

Sivanand S, Rhoades S, Jiang Q, Lee JV, Benci J, Zhang J, Yuan S, Zhao S, Carrer A, Bennett MJ, Minn AJ, Weljie AM, Greenberg RA, Wellen KE, Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination, Molecular Cell, 2017

JV Lee, K Kim, CT Berry, P Sen, T Kim, A Carrer, S Trefely, S Zhao, LE Barney, AD Schwartz, S Fernandez, SR Peyton, NW Snyder, SL Berger, BD Freedman, KE Wellen, Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+-NFAT signaling, Genes and Development, 2018

Carrer A, Parris JLD, Trefely S, Campbell SC, Norgard RJ, Egolf SS, Sidoli S, Trizzino M, Sivanand S, Sela Y, Blair IA, Garcia BA, Nathaniel W. Snyder, Stanger BZ and Kathryn E. Wellen, acetyl-CoA metabolism supports multi-step pancreatic carcinogenesis, Cancer Discovery, 2019

Sidoli S, Trefely S, Carrer A*, Integrated Analysis of Acetyl-CoA and Histone Modification via Mass Spectrometry to Investigate Metabolically Driven Acetylation, Methods Mol Biol, 2019

Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller KD, Schug ZT, Snyder NW, Gade TP, Titchenell PM, Rabinowitz JD, Wellen KE, Dietary Fructose feeds hepatic lipogenesis via microbiota-derived acetate, Nature, 2020
Paoli C & Carrer A*, Organotypic culture of acinar cells for the study of pancreatic carcinogenesis, Cancers, 2020

Grisan F, Spacci M, Paoli C, Costamagna A, Fantuz M, Martini M, Lefkimmiatis K, Carrer A*, Cholesterol activates Cyclic AMP signaling in metaplastic acinar cells, Metabolites, 2021

Calciolari B, Scapinello G, Quotti Tubi L, Piazza F, Carrer A*, Metabolic control of epigenetic rearrangements in B cell pathophysiology, Open Biology, 2022