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Rubrica

Personale Strutture

Qualifica

Professoressa Associata

Indirizzo

VIA U. BASSI, 58/B - PADOVA

Telefono

0498276237

Education:
2006 Doctor of Philosophy in Neuroscience, Faculty of Medicine and Biological Sciences, Leicester University (UK), (Supervisor: Professor Pierluigi Nicotera).
2001 Laurea degree in Biological Sciences, University of Padova (Italy). Final score: 110/110
Research and Professional Experience:
2014-present Assistant Professor, Department of Biology, University of Padova, Italy
2012-2014 Boursieres d’Excellence, Marie Curie Action Fellow. Faculté de médecine de Genève, University of Geneva, Switzerland
2011-2012 Boursieres d’Excellence, EMBO long term Fellow. Faculté de médecine de Genève, University of Geneva, Switzerland
2007-2011 Post Doctoral scientist. Medical Research Council (MRC), Centre for developmental and biomedical genetics. UK, Sheffield. (Neuroscience, Prof. A. Whitworth).
2006-2007 Post Doctoral scientist. Medical Research Council (MRC), Toxicology Unit. UK, Leicester. (Neuroscience, Prof. P. Nicotera).
2001-2006 PhD Student. Medical Research Council (MRC), Toxicology Unit. UK, Leicester. (Neuroscience, Prof. P. Nicotera).
2000-2001 Internship Student. Department of Histology Microbiology and Medical Biotechnologies. University of Padua, Italy (Development, Prof. S. Piccolo).
Awarded Fellowships:
Feb 2012-2014 Marie Curie Action
Feb 2011-Feb 2012 EMBO Long Term
Sept 2006-Sept2007 MRC Special Award for outstanding contribution to the work of the MRC Toxicology Unit over the year 2006.
Research Support:
2015-2016 Michael J Fox Foundation, RRIA (Co-PI; 125,000 $)
2014-2015 Michael J Fox Foundation, RRIA (PI; 75,000 $)
2014-2017 “Brain Gain” grant, Italian Ministry of Health (PI; 232,000 €)
2014-2017 “Ricerca Finalizzata” grant, Italian Ministry of Health (PI; 342,088 €)
2015-2017 Marie Curie- Padova University co- funded program (PISCOPIA program), which was granted to Dr Joy Chakraborty, former post doc in Ziviani lab (Supervisor; 73,218€)
2015-2017 Grant to cover a 2-years Junior postdoctoral fellowship, University of Padova (40,000€).
2015-2016 Ricerca Scientifica fondi quota EX 60% Anno 2015 (PI, 3291€). Anno 2016 (PI, 4569€)
2013-2014 Parkinson Schweiz grant for the promotion of scientific Parkinson’s Research (PI; 25,000 CHF)
Graduate Students and researcher supervision:
2015-Present Dr Sophia Von Stockum, Post Doctoral scientist, Dr Joy Chakraborty, Marie Curie-University of Padova co- funded (Piscopia program) Post Doctoral Fellow, Dr Olivier Ek, Junior Post doctoral Fellow,
2015-Present Miss Elena Marchesan, internship student, Department of Biology, University of Padova, Italy.
Review Editor:
Frontiers in Cellular Neuroscience, Biology Direct
Regular Reviewer activity:
Cell Death and Differentiation
Cell Death and Disease
Physiological Genomics
The Journal of Neuroscience
Grant reviewing activity
2016 Ad hoc peer review, Michael J. Fox foundation
2016 Ad hoc peer review, Parkinson’s UK

Avvisi

Orari di ricevimento

  • presso Dipartimento di Biologia, Complesso Vallisneri, sesto piano NORD, lab numero 59
    RIceve previo appuntamento al 045 827 6237

Pubblicazioni

Selected Peer-reviewed Publications
Research Articles
1. Mitochondrial quality control beyond PINK1/Parkin.
von Stockum S, Marchesan E, Ziviani E.
Oncotarget. 2018 9:12550-12551.
2. Postranslational modification of Parkin.
Chakraborty J., Basso V. and Ziviani E.
Biology Direct. Accepted. (2017)
3. The organelle replication connection
Ziviani E. and Scorrano L.
Nature. 538:326-327. (2016)
4. Mitochondrial dynamics and mitophagy in Parkinson's disease: A fly point of view.
Stockum S, Nardin A, Schrepfer E, Ziviani E.
Neurobiol Dis. 90:58-67. (2016)
5. Counteracting PINK/Parkin deficiency in the activation of mitophagy: a potential therapeutic intervention for Parkinson's Disease.
Nardin A, Schrepfer E, Ziviani E.
Curr Neuropharmacol. 14:250-9. (2016)
6. Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/quinone oxidoreductase 2: Implications for neuroprotection.
Janda E, Lascala A, Carresi C, Parafati M, Aprigliano S, Russo V, Savoia C, Ziviani E, Musolino V, Morani F, Isidoro C, Mollace V.
Autophagy. 11:1063-80 (2015)
7. Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy.
Ivatt RM, Sanchez-Martinez A, Godena VK, Brown S, Ziviani E, Whitworth AJ.
Proc Natl Acad Sci U S A. 111:8494-9. (2014)
8. Reduction of endoplasmic reticulum stress attenuates the defects caused by Drosophila mitofusin depletion.
Debattisti V, Pendin D, Ziviani E, Daga A, Scorrano L.
J Cell Biol. 204:303-12. (2014)
9. In Epiepsy, BAD is not really bad.
Ziviani E and Scorrano L
Neuron. 74:600-2. (2012)
10. Ryanodine receptor-2 upregulation and nicotine-mediated plasticity.
Ziviani E, Lippi G, Bano D, Munarriz E, Guiducci S, Zoli M, Young KW, Nicotera P.
EMBO J. 30:194-204. (2011)
11. Analysing the role of the PINK1/Parkin pathway in Mitophagy
Rachael I, Ziviani E and Whitworth AJ.
Journal of Neurogenetic. 24: 57-57. (2010)
12. How could Parkin-mediated ubiquitination of mitofusin promote mitophagy?
Autophagy. 6:660-2. (2010)
13. Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
Ziviani E, Tao RN, Whitworth AJ.
Proc Natl Acad Sci U S A. 107:5018-23. (2010)
14. Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1
Kira M. Holmström, Nicole Kieper, Dalila Ciceri, Fabienne C. Fiesel, Ziviani E, Alexander J. Whitworth, Hartwig Wolburg, L. Miguel Martins, Philipp J. Kahle, Rejko Krüger
Exp Cell Res. 316:1213-24. (2010)
15. Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss
Tain LS, Mortiboys H, Ziviani E, Tao RN, Bandmann O, Whitworth AJ.
Nat Neurosci. 12:1129-35. (2009)
16. The plasma membrane Na+/Ca2+ exchanger is cleaved by distinct protease families in neuronal cell death.
Bano D, Munarriz E, Chen HL, Ziviani E, Lippi G, Young KW, Nicotera P.
Ann N Y Acad Sci. 1099:451-5. (2007)





Tesi proposte

Studio della patofisiologia mitocondriale nell'ambito della malattia neurodegenerativa del morbo di Parkinson